Response Surface Methodology Optimization of Thebaine Biotransformation into Codeine and Morphine Using Bacillus sp. FAR

Financial support from the Research Council of Alzahra Universityis gratefully acknowledged. It is our honor to thank technical advising of colleagues at Medicinal Plants and Drug Research Institute of Shahid Beheshti University, Tehran, IRAN. This publication represents a component of the PhD thesis of Nazanin Ataee at the faculty of Microbiological Science of Alzahra University, Tehran, IRAN. ; Morphine and codeine are significant natural pharmaceuticals having powerful analgesic properties