نبذة مختصرة : Prirodni pigmenti dobijeni iz alge Spirulina su jedinjenja sa visokom antioksidativnom i antiinflamatornim dejstvom i imaju značajnu primenu u prehrambenoj, farmaceutskoj i kozmetčkoj industriji. Tradicionalne metode ekstrakcije koje se koriste za izolovanje ovih pigmenata uključuju upotrebu organskih rastvarača koji imaju negativan uticaj na životnu sredinu. Cilj ovog rada je izolovanje pigmenata iz spiruline primenom prirodnih eutektičkih smeša (NADES) u cilju zamene tokičnih organskih rastvarača sa alternativnim zelenim rastvaračima. Sintetisano je 10 NADESa baziranih holinijum-hloridu, betainu, glicerolu, i šećerima. Antioksidativni kapacitet ekstraktovanih pigmenata je procenjen korišćenjem DPPH testa. Najviši antioksidativni kapacitet pigmenata ekstraktovanih iz spiruline dobijen je primenom NADES na bazi betaina i glicerola. ; Natural pigments derived from the alga Spirulina are compounds with high antioxidant and anti-inflammatory effects, and they have significant applications in the food, pharmaceutical, and cosmetic industries. Traditional extraction methods used to isolate these pigments involve the use of organic solvents, which have a negative impact on the environment. The aim of this study is to isolate pigments from Spirulina using natural deep eutectic solvents (NADES) to replace toxic organic solvents with alternative green solvents. Ten NADESs were synthesized based on choline chloride, betaine, glycerol and sugars. The antioxidant capacity of extracted pigments was evaluated using DPPH test. The highest antioxidative capacity of pigments extracted from spirulina was obtained using NADES based on betaine and glycerol. ; 60th Meeting of the Serbian Chemical Society; June 8-9, 2024, Niš, Serbia.
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