Contributors: Ali, M. Glasgow Caledonian Univ, NMAHP Res Unit, A433 Govan Mbeki Bldg, Glasgow G4 0BA, Lanark, Scotland; Brady, M. C. Glasgow Caledonian Univ, NMAHP Res Unit, A433 Govan Mbeki Bldg, Glasgow G4 0BA, Lanark, Scotland; Ben Basat, A. Lifshitz Ariel Univ, Dept Commun Disorders, Ariel, Israel; Berthier, M. Univ Malaga, Inst Invest Biomed Malaga IBIMA, Cognit Neurol & Aphasia Unit, Ctr Invest Medicosanitarias, Malaga, Spain; Davila, G. Univ Malaga, Inst Invest Biomed Malaga IBIMA, Cognit Neurol & Aphasia Unit, Ctr Invest Medicosanitarias, Malaga, Spain; Blom Johansson, M. Uppsala Univ, Dept Neurosci, Speech Language Pathol, Uppsala, Sweden; Breitenstein, C. Univ Munster, Dept Neurol, Inst Translat Neurol, Munster, Germany; Cadilhac, D. A. Monash Univ, Sch Clin Sci, Dept Med, Monash Hlth, Melbourne, Vic, Australia; Constantinidou, F. Univ Cyprus Nicosia, Dept Psychol, Nicosia, Cyprus; Constantinidou, F. Univ Cyprus Nicosia, Ctr Appl Neurosci, Nicosia, Cyprus; Cruice, M. City Univ London, London, England; Davila, G. Univ Malaga, Fac Psychol & Speech Therapy, Area Psychobiol, Malaga, Spain; Gandolfi, M. Univ Verona, Dept Neurosci Biomed & Movement Sci, Verona, Italy; Gil, M. Loewenstein Hosp & Rehabil Ctr, Dept Commun Disorders, Raanana, Israel; Grima, R. Univ Malta Imsida, Dept Commun Therapy, Fac Hlth Sci, Msida, Malta; Godecke, E. Edith Cowan Univ, Sch Med & Hlth Sci, Churchlands, WA, Australia; Godecke, E. Sir Charles Gairdner Hosp, Speech Pathol Dept, Nedlands, WA, Australia; Godecke, E. Ctr Res Excellence Aphasia Recovery & Rehabil, Melbourne, Vic, Australia; Jesus, L. Univ Aveiro, Sch Hlth Sci ESSUA, Aveiro, Portugal; Jesus, L. Univ Aveiro, Inst Elect & Informat Engn Aveiro IEETA, Aveiro, Portugal; Jiminez, L. Martinez Univ Talca, Talca, Chile; Kambanaros, M. Univ South Australia, Allied Hlth & Human Performance, Adelaide South, Australia; Kukkonen, T. Tampere Univ Hosp, Pirkanmaa Hosp Dist, Dept ENT Phoniatry, Tampere, Finland; Laska, A. Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Stockholm, Sweden; Mavis, I Anadolu Univ, Speech & Language Therapy Dept, Eskisehir, Turkey; Mc Menamin, R. Natl Univ Ireland, Sch Hlth Sci, Discipline Speech & Language Therapy, Galway, Ireland; Mendez-Orellana, C. Pontificia Univ Catolica Chile, Fac Med, Dept Ciencias Salud, Carrera Fonoaudiol, Santiago, Chile; Obrig, H. Univ Hosp Leipzig, Clin Cognit Neurol, Leipzig, Germany; Obrig, H. MPI Human Cognit & Brain Sci, Leipzig, Germany; Ostberg, P. Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden; Robson, H. UCL, Psychol & Language Sci, London, England; Sage, K. Manchester Metropolitan Univ, Fac Hlth Psychol & Social Care, Dept Nursing, Manchester, Lancs, England; Van De Sandt-koenderman, M. Rijndam Rehabil Ctr, Dept Rehabil Med, Rotterdam, Netherlands; Wielaert, S. Rijndam Rehabil Ctr, Dept Rehabil Med, Rotterdam, Netherlands; Van De Sandt-koenderman, M. Erasmus MC, Rotterdam, Netherlands; Wielaert, S. Erasmus MC, Rotterdam, Netherlands; Sprecht, K. Univ Bergen, Fac Psychol, Dept Biol & Med Psychol, Bergen, Norway; Visch-Brink, E. Erasmus MC, Dept Neurol & Neurosurg, Rotterdam, Netherlands; Wehling, E. Haukeland Hosp, Dept Phys Med & Rehabil, Bergen, Norway; Wallace, S. J. Univ Queensland, Sch Hlth & Rehabil Sci, Queensland Aphasia Res Ctr, Brisbane, Qld, Australia; Williams, L. J. Univ Edinburgh, Usher Inst, Edinburgh, Midlothian, Scotland; Tavistock Trust for Aphasia
نبذة مختصرة : Background: We require high-quality information on the current burden, the types of therapy and resources available, methods of delivery, care pathways and long-term outcomes for people with aphasia. Aim: To document and inform international delivery of post-stroke aphasia treatment, to optimise recovery and reintegration of people with aphasia. Methods & Procedures: Multi-centre, prospective, non-randomised, open study, employing blinded outcome assessment, where appropriate, including people with post-stroke aphasia, able to attend for 30 minutes during the initial language assessment, at first contact with a speech and language therapist for assessment of aphasia at participating sites. There is no study-mandated intervention. Assessments will occur at baseline (first contact with a speech and language therapist for aphasia assessment), discharge from Speech and Language Therapy (SLT), 6 and 12-months post-stroke. Our primary outcome is changed from baseline in the Amsterdam Nijmegen Everyday Language Test (ANELT/Scenario Test for participants with severe verbal impairments) at 12-months post-stroke. Secondary outcomes at 6 and 12 months include the Therapy Outcome Measure (TOMS), Subjective Index of Physical and Social Outcome (SIPSO), Aphasia Severity Rating Scale (ASRS), Western Aphasia Battery Aphasia Quotient (WAB-AQ), stroke and aphasia quality of life scale (SAQoL-39), European Quality of Life Scale (EQ-5D), lesion description, General Health Questionnaire (GHQ-12), resource use, and satisfaction with therapy provision and success. We will collect demography, clinical data, and therapy content. Routine neuroimaging and medication administration records will be accessed where possible; imaging will be pseudonymised and transferred to a central reading centre. Data will be collected in a central registry. We will describe demography, stroke and aphasia profiles and therapies available. International individual participant data (IPD) meta-analyses will examine treatment responder rates based on ...
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