Ozone in Dentistry: An Updated Overview of Current Applications and Future Perspectives

Purpose of Review Oxygen-ozone therapy (OOT) is increasingly applied due to its multiple therapeutic effects, but it is still controversial in the medical community. This review provides a comprehensive overview of the recent clinical literature on OOT in dentistry, exploring its efficacy and current issues. Recent Findings OOT has a wide range of applications in dentistry, including caries management, endodontics, periodontics, and oral surgery. Overall, the results are promising with very limited adverse effects. The formulations used include gaseous ozone, ozonized water, ozonized gel, and ozonization of various products. A large methodologic heterogeneity currently prevents definitive conclusions and meaningful comparisons between different protocols. Summary Although not conclusive, current evidence suggests that OOT may offer some advantages as an adjunctive or alternative treatment option in certain clinical conditions. Future research should aim to standardize the reporting methodology of OOT protocols