نبذة مختصرة : Background Left ventricular hypertrophy (LVH) is frequently seen in association with arterial hypertension and indicates poor prognosis. This study aimed to determine the prevalence of LVH and associated factors in a multiethnic population from Mauritius. Methods Population-based health surveys were performed in 2009 and 2015 and included in total 8961 individuals aged 35–75 years with recorded 12-lead ECG. LVH was defined according to three criteria: Sokolow-Lyon, Cornell voltage and Cornell product. Data were collected about health and lifestyle behaviour. Anthropometry and blood pressure were measured. Fasting levels of blood lipids and glucose were determined, oral glucose tolerance test was performed in people without glucose-lowering medications. Results The age-standardised prevalence of LVH was 9% (n=875) according to any of the three ECG criteria. Individuals with LVH were older, more likely to have hypertension, diabetes, known cardiovascular disease (CVD) and elevated levels of cholesterol and creatinine. Further, they were more likely to be of African descent (Creole) and have lower educational level. In a multivariable model, Creole (OR (95% CI)) (1.56 (1.33 to 1.83)), low educational level (1.49 (1.28 to 1.75)), hypertension (3.01 (2.55 to 3.56)), known CVD (1.42 (1.11 to 1.83)) and elevated creatinine (1.08 (1.03 to 1.14)) remained associated with LVH. Individuals with non-treated or uncontrolled hypertension had a higher risk for LVH (3.09 (95% CI 2.57 to 3.71) and 4.07 (95% CI 3.29 to 5.05), respectively), than individuals with well controlled hypertension or normotension. Conclusion LVH occurs more frequently in individuals with hypertension, as well as in individuals with African ancestry and/or low education level. ; Peer reviewed
Relation: We are most grateful to the study participants for volunteering their valuable time, and to the staff at the Ministry of Health and Quality of Life in Mauritius for organising and conducting the Mauritius studies. We would also like to thank Regina Reklaitiene and Ricardas Radisauskas, the ECG coders in Kaunas, Lithuania and Mirjam Butler for data management in Umeå, Sweden. The Mauritius NCD study was organised by the Mauritian Ministry of Health and Wellness in collaboration with the WHO (WHO, Geneva, Switzerland), Baker Heart and Diabetes Institute (formerly the International Diabetes Institute, Melbourne, Australia), the University of Newcastle upon Tyne (UK), the National Public Health Institute (Helsinki, Finland) and Umeå University (Umeå, Sweden). Grants from the Västerbotten County Council (ALF) (grant number RV-967561), and Swedish Heart and Lung Foundation (grant number 20130630) made this substudy possible. The Mauritius NCD study was organised by the Mauritian Ministry of Health and Wellness in collaboration with the WHO (WHO, Geneva, Switzerland), Baker Heart and Diabetes Institute (formerly the International Diabetes Institute, Melbourne, Australia), the University of Newcastle upon Tyne (UK), the National Public Health Institute (Helsinki, Finland) and Umeå University (Umeå, Sweden). Grants from the Västerbotten County Council (ALF) (grant number RV-967561), and Swedish Heart and Lung Foundation (grant number 20130630) made this substudy possible.; Taki , H , Tuomilehto , J , Zimmet , P , Tamosiunas , A , Kowlessur , S , Magliano , D J , Shaw , J E , Söderberg , S & Nilsson , U 2023 , ' Left ventricular hypertrophy : an ECG-based study of prevalence and risk factors in a multiethnic population ' , Open Heart , vol. 10 , no. 2 , e002495 . https://doi.org/10.1136/openhrt-2023-002495; http://hdl.handle.net/10138/568443; 6cef3f9e-8f30-45ce-b61e-8979d4bd2b1e; 85177882151; 001102573300003
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