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Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma : Scandinavian Journal of Urology

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      Urologian yksikkö; University of Helsinki; Helsinki University Hospital Area; HUS Abdominal Center; Clinicum; Department of Surgery; Department of Clinical Chemistry and Hematology; Medicum; Department of Oncology; HUS Comprehensive Cancer Center
    • بيانات النشر:
      Taylor and Francis Ltd.
    • الموضوع:
      2020
    • Collection:
      Helsingfors Universitet: HELDA – Helsingin yliopiston digitaalinen arkisto
    • نبذة مختصرة :
      Objective Tumour associated trypsin inhibitor (TATI) is a peptide that is a marker for several tumours. TATI may also behave as an acute phase reactant in severe inflammatory disease. Overexpression of TATI predicts an unfavourable outcome for many cancers. This study aimed to evaluate the prognostic value of pre- and postoperative concentration of TATI in serum (S-TATI) of patients with renal cell carcinoma (RCC). Materials and methods S-TATI was determined by time resolved immunofluorometric assay in preoperative and postoperative samples that were collected from 132 RCC patients, who underwent partial or complete nephrectomy in Helsinki University Hospital from May 2005 to July 2010. Results Preoperative S-TATI was significantly associated with tumour stage, lymph-node involvement, metastatic stage, Chronic Kidney Disease Stage (CKD grade), and preoperative C-reactive protein level (p? ; Peer reviewed
    • File Description:
      application/pdf
    • Relation:
      Tornberg , S V , Nisen , H , Järvinen , P , Järvinen , R , Kilpeläinen , T P , Taari , K , Stenman , U-H & Visapää , H 2020 , ' Serum tumour associated trypsin inhibitor, as a biomarker for survival in renal cell carcinoma : Scandinavian Journal of Urology ' , Scandinavian Journal of Urology , vol. 54 , no. 5 , pp. 413-419 . https://doi.org/10.1080/21681805.2020.1798501; RIS: urn:1FAAA3271374E9C7134804DDE48D2788; ORCID: /0000-0002-0077-4896/work/83054553; http://hdl.handle.net/10138/321083; 0b239139-2258-4223-ac2a-1e2e9ac12e29; 000555203900001
    • Rights:
      cc_by_nc_nd ; info:eu-repo/semantics/openAccess ; openAccess
    • الرقم المعرف:
      edsbas.7FD030B4