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Gene drives to fight malaria: current state and future directions

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  • معلومة اضافية
    • بيانات النشر:
      Taylor & Francis
    • الموضوع:
      2018
    • Collection:
      Imperial College London: Spiral
    • نبذة مختصرة :
      Self-propagating gene drive technologies have a number of desirable characteristics that warrant their development for the control of insect pest and vector populations, such as the malaria-transmitting mosquitoes. Theoretically easy to deploy and self-sustaining, these tools may be used to generate cost-effective interventions that benefit society without obvious bias related to wealth, age or education. Their species-specific design offers the potential to reduce environmental risks and aim to be compatible and complementary with other control strategies, potentially expediting the elimination and eradication of malaria. A number of strategies have been proposed for gene-drive based control of the malaria mosquito and recent demonstrations have shown proof-of-principle in the laboratory. Though several technical, ethical and regulatory challenges remain, none appear insurmountable if research continues in a step-wise and open manner.
    • ISSN:
      2047-7724
    • Relation:
      Pathogens and Global Health; http://hdl.handle.net/10044/1/64948; https://dx.doi.org/10.1080/20477724.2018.1438880
    • الرقم المعرف:
      10.1080/20477724.2018.1438880
    • الدخول الالكتروني :
      http://hdl.handle.net/10044/1/64948
      https://doi.org/10.1080/20477724.2018.1438880
    • Rights:
      © 2018 The Author(s). This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited, and is not altered, transformed, or built upon in any way.
    • الرقم المعرف:
      edsbas.7CD45238