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Asthma control assessed in the EGEA epidemiological survey and health-related quality of life.

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  • معلومة اضافية
    • Contributors:
      Institut d'oncologie/développement Albert Bonniot de Grenoble (INSERM U823); Université Joseph Fourier - Grenoble 1 (UJF)-Centre Hospitalier Universitaire CHU Grenoble (CHUGA)-EFS-Institut National de la Santé et de la Recherche Médicale (INSERM); Centre de recherche en épidémiologie et santé des populations (CESP); Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Sud - Paris 11 (UP11)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM); Département pneumologie et addictologie Montpellier; Hôpital Arnaud de Villeneuve CHRU Montpellier; Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier); Service de pneumologie Centre Hospitalier Lyon Sud - HCL; Centre Hospitalier Lyon Sud CHU - HCL (CHLS); Hospices Civils de Lyon (HCL)-Hospices Civils de Lyon (HCL); CHU Trousseau APHP; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU); Physiopathologie et Epidemiologie de l'Insuffisance Respiratoire; Université Paris Diderot - Paris 7 (UPD7)-Institut National de la Santé et de la Recherche Médicale (INSERM); Clinique de pneumologie; Centre Hospitalier Universitaire CHU Grenoble (CHUGA); Service de Pneumologie Allergologie CHU Necker; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpital Necker - Enfants Malades AP-HP; Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP); Service de Pneumologie Grenoble; Centre Hospitalier Universitaire CHU Grenoble (CHUGA)-Hôpital Michallon; CIBER en Epidemiologia y Salud Pública; Center for Research in Environmental Epidemiology (CREAL); Universitat Pompeu Fabra Barcelona (UPF)-Catalunya ministerio de salud; IMIM-Hospital del Mar; Generalitat de Catalunya = Generalidad de Cataluña = Government of Catalonia; Département de pédiatrie; The EGEA study was supported in part by grants from Merck Sharp & Dohme (MSD); Hospital program of clinical research (PHRC)-Paris; National Research Agency - Health environment, healthwork program; National Research Agency (ANR)- Biological collections for health program; French Agency of health safety, environment and work (AFSSET); the national scientific committee of the medico-technology support at home (AGIR à dom) and the Isere committee against respiratory diseases (COMARES).
    • بيانات النشر:
      HAL CCSD
      Elsevier
    • الموضوع:
      2012
    • Collection:
      Hospices Civils de Lyon (HCL): HAL
    • نبذة مختصرة :
      International audience ; BACKGROUND: The aims were to assess 1) the relationship of asthma control assessed by combining epidemiological survey questions and lung function to Health-Related Quality of Life (HRQL) and 2) whether individuals with controlled asthma reach similar generic HRQL levels as individuals without asthma. METHODS: The analysis included 584 individuals without asthma and 498 with asthma who participated in the follow-up of the Epidemiological study on Genetics and Environment of Asthma (EGEA). Asthma control was assessed from survey questions and lung function, closely adapted from the 2006-2009 Global Initiative for Asthma guidelines. The Asthma Quality of Life Questionnaire (AQLQ, scores range:1-7) and the generic SF-36 (scores range: 0-100) were used. RESULTS: Adjusted mean total AQLQ score decreased by 0.5 points for each asthma control steps (6.4, 5.9 and 5.4 for controlled, partly-controlled and uncontrolled asthma respectively, p < 0.0001). The differences in SF-36 scores between individuals with controlled asthma and those without asthma were minor and not significant for the PCS (-1, p = 0.09), borderline significant for the MCS (-1.6, p = 0.05) and small for the 8 domains (<5.1) although statistically significant for 4 domains. CONCLUSION: These results support the discriminative properties of the proposed asthma control grading system and its use in epidemiology.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/22365669; inserm-00742663; https://inserm.hal.science/inserm-00742663; https://inserm.hal.science/inserm-00742663/document; https://inserm.hal.science/inserm-00742663/file/siroux_rm_2012_sp.pdf; PUBMED: 22365669
    • الرقم المعرف:
      10.1016/j.rmed.2012.01.009
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.7B481D5E