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Effect of mood on long-term disability in younger stroke survivors: results from the Psychosocial Outcomes In StrokE (POISE) study

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  • معلومة اضافية
    • بيانات النشر:
      Taylor & Francis
    • الموضوع:
      2021
    • Collection:
      UNSW Sydney (The University of New South Wales): UNSWorks
    • نبذة مختصرة :
      Background & Purpose: Anxiety and depression are common among stroke survivors, and their effect on long-term outcome remains unknown in those under 65 years of age. We investigated the association between early anxiety/depression after stroke and 12-month disability, and whether this is modified by sex. Methods: The Psychosocial Outcomes In StrokE (POISE) study was a prospective observational cohort study that recruited 441 younger (< 65 years) stroke survivors ≤28 days of acute stroke. Anxiety and depression were assessed using the Hospital Anxiety and Depression Scale, and disability using the World Health Organization Disability Assessment Scale version II (WHODAS-II). Associations between baseline anxiety/depression, and disability at 12-months was tested using analysis of covariance. Subgroup analysis was conducted using interaction term. Results: 92 (25%) had anxiety and 53 (14%) depression at baseline. Multivariable models showed significant association between baseline anxiety and 12-month disability (WHODAS-II score 15.24 vs. 11.49, p < .05). Those with anxiety had more impairment in ‘cognition’ (WHODAS-II score 18.26 vs. 8.71, p < .001), ‘getting along’ (WHODAS-II score 11.87 vs. 7.42, p < .05) and ‘participation’ (WHODAS-II score 22.37 vs. 15.92, p < .005) WHODAS-II. No significant relationship was found between baseline depression and long-term disability. There was no differential effect of anxiety by sex found in this study. Conclusions: Post-stroke anxiety has an adverse effect on disability at one year among young stroke survivors.
    • File Description:
      application/vnd.openxmlformats-officedocument.wordprocessingml.document
    • Relation:
      http://hdl.handle.net/1959.4/unsworks_77403; https://unsworks.unsw.edu.au/bitstreams/aa47c306-7d0c-406e-babf-e7d84ea0c742/download; https://doi.org/10.1080/10749357.2021.1922802
    • الرقم المعرف:
      10.1080/10749357.2021.1922802
    • Rights:
      open access ; https://purl.org/coar/access_right/c_abf2 ; CC-BY-NC-ND ; https://creativecommons.org/licenses/by-nc-nd/4.0/ ; free_to_read ; “This is an Accepted Manuscript version of the following article, accepted for publication in Topics in Stroke Rehabilitation. C Liang, AJ Van Laar Veth, Q Li, D Zheng & ML Hackett (2021) Effect of mood on long-term disability in younger stroke survivors: results from the Psychosocial Outcomes In StrokE (POISE) study, Topics in Stroke Rehabilitation, DOI:10.1080/10749357.2021.1922802. It is deposited under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited.”
    • الرقم المعرف:
      edsbas.777F72D3