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Inherited Chromosomally Integrated Human Herpesvirus 6 : An Unexpected Finding in a Septic Neonate

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  • معلومة اضافية
    • Contributors:
      L. Pugni; C. Pietrasanta; A. Ronchi; G. Lunghi; L. Pellegrinelli; F. Mosca; G. Campanini; F. Baldanti
    • بيانات النشر:
      Lippincott Williams & Wilkins
    • الموضوع:
      2021
    • Collection:
      The University of Milan: Archivio Istituzionale della Ricerca (AIR)
    • نبذة مختصرة :
      Human herpesvirus 6 (HHV-6) can integrate its genome in human chromosomes and be germline transmitted (inherited chromosomally integrated HHV-6). We report a case of chromosomally integrated HHV-6 inherited from the mother unexpectedly diagnosed in a septic neonate. Since HHV-6 has recently been included in multiplex polymerase chain reaction assays for meningitis/encephalitis, diagnosing inherited chromosomally integrated HHV-6 status is essential to avoid misdiagnosis of active HHV-6 infection and unnecessary antiviral treatment.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/33284253; info:eu-repo/semantics/altIdentifier/wos/WOS:000597406200029; volume:40; issue:1; firstpage:74; lastpage:75; numberofpages:2; journal:THE PEDIATRIC INFECTIOUS DISEASE JOURNAL; http://hdl.handle.net/2434/797706; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85097584253
    • الرقم المعرف:
      10.1097/INF.0000000000002905
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.745C7CBC