3D CT volumetric analysis of the lung in COPD patients: Comparison with pulmonary function tests

Background: Retro and prospective comparative analytical study will be done over a 2-year period on patients with a multidisciplinary diagnosis of chronic obstructive pulmonary disease at the radiology department of Ain Shams University Hospitals. The aim of the study: Toassess the role of the new CT lung analysis in quantitative assessment of chronic obstructive lung disease. The procedures: Patients will be subjected to CT chest without contrast then 3D models will be reconstructed using a software that allows automatic segmentation of each lung lobes and volume calculation, and giving each lung zone a Goddard score to determine the severity. The instruments: Patients will be assessed by the pulmonary function tests and body plethysmography. The results: The results will be collected and compared together. Data analysis will be performed using IBM statistical program for social science, version 22.0 (SPSS, 2013; IBM Corp., USA). Quantitative and qualitative data will be expressed as mean±SD, frequencies, and percentages. In addition, the relationship between total lung capacity (TLC), CT lung volume, and percentage LAA will be assessed and considered significant when the P-value is less than 0.05.