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Comparison of the Lunar Prodigy and Stratos DR dual-energy X-ray absorptiometers to assess regional bone mineral density

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  • معلومة اضافية
    • Contributors:
      Physiologie & médecine expérimentale du Cœur et des Muscles U 1046 (PhyMedExp); Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM); Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier); Université de Montpellier (UM); Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)
    • بيانات النشر:
      HAL CCSD
      Elsevier
    • الموضوع:
      2022
    • Collection:
      Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe)
    • نبذة مختصرة :
      International audience ; Purpose: The first objective of the study was to assess the agreement between the Stratos DR (DMS) and the GE Prodigy (GE) DXAs in determining femoral neck, total hip and lumbar spine aBMD. The second objective was to assess the potential impact of leg positioning (hip flexed at 90° or not) on lumbar spine aBMD.Methods: Forty-six individuals (n=42 women, 91.3%), with a mean age of 59.7 ± 13 years and mean BMI of 23.8 ± 4.7 kg/m², were scanned consecutively on the same day using the two devices. In a subgroup (n=30), two consecutive Stratos DR scans (with hip flexed at 90° or not) at the lumbar spine were conducted. Predictive equations for hip and lumbar spine aBMD were derived from linear regression of the data.Results: Correlation coefficients for aBMD measured with the two DXAs were characterised by an R² of 0.76 for the femoral neck, 0.89 for the total hip, and 0.86 for the lumbar spine. However, the derived equations for aBMD determination showed an intercept significantly different from 0 for hip aBMD, and a slope significantly different from 1 for lumbar spine aBMD. These results highlight a bias between the two measurements, thus requiring the determination of specific cross-calibration equations for hip and lumbar spine, femoral neck excepted. When compared with values on the Prodigy, mean aBMD on the Stratos DR was higher at the femoral neck (+4.8%, p<0.001) and total hip (+9.6%, p<0.001) and lower at L2-L4 (-8.8%, p<0.001). The coefficient of variation (CV%) for the two consecutive measures at lumbar spine (with different positioning) with the Stratos DR was 2.9%.Conclusions: The difference in aBMD measured with the two DXAs illustrates the need to define cross-calibration equations when comparing data across systems in order to avoid erroneous conclusions.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/35909031; hal-03737423; https://hal.science/hal-03737423; https://hal.science/hal-03737423/document; https://hal.science/hal-03737423/file/Maimoun_al_J-Clin-Densit_2022.pdf; PUBMED: 35909031; WOS: 000895946200017
    • الرقم المعرف:
      10.1016/j.jocd.2022.07.001
    • الدخول الالكتروني :
      https://hal.science/hal-03737423
      https://hal.science/hal-03737423/document
      https://hal.science/hal-03737423/file/Maimoun_al_J-Clin-Densit_2022.pdf
      https://doi.org/10.1016/j.jocd.2022.07.001
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.6F46CC3A