Contributors: Rongeurs Sauvages, Risques Sanitaires et Gestion des Populations - UR 1233 (RS2GP); VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Unité Mixte de Recherche d'Épidémiologie des maladies Animales et zoonotiques (UMR EPIA); Ecole Polytechnique d'Abomey Calavi (EPAC); Université d’Abomey-Calavi = University of Abomey Calavi (UAC); Laboratoire des Leptospires; VetAgro Sup - Institut national d'enseignement supérieur et de recherche en alimentation, santé animale, sciences agronomiques et de l'environnement (VAS); Animal, Santé, Territoires, Risques et Ecosystèmes (UMR ASTRE); Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE); Département Systèmes Biologiques (Cirad-BIOS); Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad); Centre de Biologie pour la Gestion des Populations (UMR CBGP); Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-Institut de Recherche pour le Développement (IRD France-Sud )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Institut Agro Montpellier; Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Université de Montpellier (UM); Institut Pasteur de Madagascar; Réseau International des Instituts Pasteur (RIIP); This study was funded by VetAgroSup, INRAE and IRD.
نبذة مختصرة : The peer review history for this article is available at: https://publons.com/publon/10.1002/vms3.143The data that supports the findings of this study are available in the supplementary material of this article.We assert that the sampling protocol adhered to French and European legislation on the treatment and usage of animals (Directive2010/63/EC and French Administrative Decision 118-2013/02/01). The field work was conducted in accordance with the procedure approved by VetAgroSup Ethic Committee (agreementn◦2349). ; International audience ; BACKGROUND: Leptospirosis is a zoonotic disease. It is particularly prevalent in tropical countries and has major consequences for human and animal health. In Benin, the disease's epidemiology remains poorly understood, especially in livestock, for which data are lacking.OBJECTIVES: To characterise Leptospira seroprevalence and locally circulating serogroups in livestock from Cotonou and to estimate the prevalence of Leptospira renal carriage in cattle.METHODS: We conducted a cross-sectional study in February 2020 during which livestock were sampled at an abattoir and in an impoverished city district. We analysed blood samples from 279 livestock animals (i.e. cattle, sheep, goats and pigs) using the microscopic agglutination test. Additionally, samples of renal tissue from 100 cattle underwent 16s rRNA (rrs) real-time PCR analysis.RESULTS: For the 131 cattle, 85 sheep, and 50 goats tested, seroprevalence was 18% (95% confidence interval [CI] [12%, 26%]), 9% (95% CI [4%, 17%] and 2% (95% CI [0%, 9%]), respectively, and most of the seropositive animals were associated with 1:100 titres. All 13 pigs were seronegative. Leptospira DNA was found in the renal tissue of 10% (95% CI [5%, 18%]) of the cattle tested (n=100). Leptospira borgpetersenii was the main species present (n=7), but Leptospira interrogans (n=2) and Leptospira kirschneri (n=1) were also detected. Various serogroups (Canicola, Grippotyphosa, Sejroe, Icterohaemorrhagiae, Pomona, Pyrogenes, Australis and ...
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