Characterization of risk factors and occurrence of death in newborns diagnosed with neonatal sepsis in a Neonatal Intensive Care Unit ; Caracterización de factores de riesgo y ocurrencia de muerte en recién-nacidos con diagnóstico de sepsis neonatal en una Unidad de Cuidados Intensivos Neonatales ; Caracterização dos fatores de risco e ocorrência de óbito em recém-nascidos com diagnóstico de sepse neonatal em uma Unidade de Terapia Intensiva Neonatal

Neonatal sepsis is one of the leading causes of death in newborns. Prior knowledge of risk factors is essential to prevent morbidity and mortality. This study aims to characterize the observed risk factors and their relationship with the occurrence of death in newborns diagnosed with sepsis. A cross-sectional study was carried out with the analysis of 712 participants hospitalized from September 2018 to June 2020. 410 neonates were included, with a higher proportion being males, born with artificial delivery and low birth weight. The prevalence of death observed was 6.3%, occurring especially among those with moderate and extreme prematurity, those born to teenage mothers or mothers over forty, those with hyperthermia, low weight, bradycardia and longer hospital stays. There was a low frequency of blood cultures performed. Although there was no predominance of typical clinical findings of sepsis, such as hypothermia, changes in the leukogram, platelet count and CRP levels, the robust findings of a greater association of extreme low birth weight, hyperthermia and tachypnea to a higher frequency of death reinforce the quality of the data obtained. ; La sepsis neonatal es una de las principales causas de muerte en los recién nacidos. El conocimiento previo de los factores de riesgo es fundamental para prevenir la morbimortalidad. Este estudio tiene como objetivo caracterizar los factores de riesgo observados y su relación con la ocurrencia de muerte en recién nacidos con diagnóstico de sepsis. Se realizó un estudio transversal con el análisis de 712 participantes hospitalizados desde septiembre de 2018 hasta junio de 2020. Se incluyeron 410 neonatos, con una mayor proporción del sexo masculino, nacidos con parto artificial y bajo peso al nacer. La prevalencia de óbito observada fue del 6,3%, siendo significativa sobre todo entre aquellos con prematuridad moderada y extrema, los nacidos de madre adolescente y los mayores de 40 años, aquellos con hipertermia, bajo peso, bradicardia y estancias hospitalarias ...