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Force-induced unfolding of an antibiotic-bound outer-membrane protein.

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  • معلومة اضافية
    • Contributors:
      UCL - SST/LIBST - Louvain Institute of Biomolecular Science and Technology
    • الموضوع:
      2022
    • Collection:
      DIAL@UCL (Université catholique de Louvain)
    • نبذة مختصرة :
      In this issue of Structure, Ritzmann et al. characterize the unfolding of the β-barrel assembly machinery component BamA with single-molecule force spectroscopy and reveal how an antibiotic changes BamA's mechanical properties and inhibits its activity. This work helps us understand the effects antibiotics have on Gram-negative outer membrane proteins.
    • ISSN:
      09692126
      1878-4186
    • Relation:
      boreal:261203; http://hdl.handle.net/2078.1/261203; info:pmid/35245432; urn:ISSN:09692126; urn:EISSN:1878-4186
    • الرقم المعرف:
      10.1016/j.str.2022.02.009
    • الدخول الالكتروني :
      http://hdl.handle.net/2078.1/261203
      https://doi.org/10.1016/j.str.2022.02.009
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.6601F312