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Specific IgA, But Not IgG, in Human Milk From COVID-19-Infected Mothers Neutralizes SARS-CoV-2

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  • معلومة اضافية
    • بيانات النشر:
      Wolters Kluwer Health
    • الموضوع:
      2024
    • Collection:
      Universidad Complutense de Madrid (UCM): E-Prints Complutense
    • نبذة مختصرة :
      This study highlights the importance of human milk in providing anti-severe acute respiratory syndrome coronavirus 2 immunity to newborns. The highest protective activity of human milk against COVID-19 was found in colostrum from infected mothers. Neutralizing activity was associated with high levels of specific IgA. Depletion of IgA, but not IgG, from milk samples completely abolished the ability of human milk to neutralize severe acute respiratory syndrome coronavirus 2. ; Instituto de Salud Carlos III ; Depto. de Nutrición y Ciencia de los Alimentos ; Fac. de Veterinaria ; TRUE ; pub
    • File Description:
      application/pdf
    • ISSN:
      0891-3668
      1532-0987
    • Relation:
      info:eu-repo/grantAgreement/ISCIII/COV20/01046; info:eu-repo/grantAgreement/MINECO//RD16%2F0022%2F0003/ES/RED DE SALUD MATERNO-INFANTIL Y DEL DESARROLLO/; Macchiaverni, Patricia PhD*,†; Lloyd, Megan PhD*,†,‡; Masters, Laura PhD‡; Divakara, Nivedithaa MS*,†; Panta, Kritu PhD‡; Imrie, Allison PhD‡; Sánchez-García, Laura MD§; Pellicer, Adelina PhD§; Rodriguez, Juan M. MD, PhD¶; Verhasselt, Valerie MD, PhD*,†. Specific IgA, But Not IgG, in Human Milk From COVID-19-Infected Mothers Neutralizes SARS-CoV-2. The Pediatric Infectious Disease Journal 43(6):p 532-535, June 2024. DOI:10.1097/INF.0000000000004291; https://hdl.handle.net/20.500.14352/105286
    • الرقم المعرف:
      10.1097/INF.0000000000004291
    • Rights:
      Attribution-NonCommercial-NoDerivatives 4.0 International ; http://creativecommons.org/licenses/by-nc-nd/4.0/ ; open access
    • الرقم المعرف:
      edsbas.653B0337