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Malaria after international travel: a GeoSentinel analysis, 2003-2016.

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  • معلومة اضافية
    • بيانات النشر:
      Springer Science and Business Media LLC
      //dx.doi.org/10.1186/s12936-017-1936-3
      Malar J
    • الموضوع:
      2017
    • Collection:
      Apollo - University of Cambridge Repository
    • نبذة مختصرة :
      BACKGROUND: More than 30,000 malaria cases are reported annually among international travellers. Despite improvements in malaria control, malaria continues to threaten travellers due to inaccurate perception of risk and sub-optimal pre-travel preparation. METHODS: Records with a confirmed malaria diagnosis after travel from January 2003 to July 2016 were obtained from GeoSentinel, a global surveillance network of travel and tropical medicine providers that monitors travel-related morbidity. Records were excluded if exposure country was missing or unascertainable or if there was a concomitant acute diagnosis unrelated to malaria. Records were analyzed to describe the demographic and clinical characteristics of international travellers with malaria. RESULTS: There were 5689 travellers included; 325 were children <18 years. More than half (53%) were visiting friends and relatives (VFRs). Most (83%) were exposed in sub-Saharan Africa. The median trip duration was 32 days (interquartile range 20-75); 53% did not have a pre-travel visit. More than half (62%) were hospitalized; children were hospitalized more frequently than adults (73 and 62%, respectively). Ninety-two per cent had a single Plasmodium species diagnosis, most frequently Plasmodium falciparum (4011; 76%). Travellers with P. falciparum were most frequently VFRs (60%). More than 40% of travellers with a trip duration ≤7 days had Plasmodium vivax. There were 444 (8%) travellers with severe malaria; 31 children had severe malaria. Twelve travellers died. CONCLUSION: Malaria remains a serious threat to international travellers. Efforts must focus on preventive strategies aimed on children and VFRs, and chemoprophylaxis access and preventive measure adherence should be emphasized.
    • File Description:
      Electronic; application/pdf
    • Relation:
      https://www.repository.cam.ac.uk/handle/1810/294943
    • الرقم المعرف:
      10.17863/CAM.42030
    • Rights:
      Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/
    • الرقم المعرف:
      edsbas.60A330DB