Contributors: Sánchez,MI; Mascareñas,JL; Vázquez,ME Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, Santiago de Compostela, Spain. Sugiura,A Montreal Neurological Institute, McGill University, Montreal, QC, Canada. Sugiura,A Department of Neurology and Neurosurgery, McGill University, Montreal, QC, Canada. Vida,Y; Pérez-Inestrosa,E Centro Andaluz de Nanomedicina y Biotecnología-BIONAND. Campanillas, Málaga, Spain. Martínez-Costas,J Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Bioquímica y Biología Molecular, Universidade de Santiago de Compostela, Santiago de, Compostela, Spain. Vida,Y; Pérez-Inestrosa,E Universidad de Málaga-IBIMA, Departamento de Química Orgánica, Málaga, Spain.; The support was given by the Spanish grants BFU2013-43513-R, SAF2016-76689-R, CTQ2015-70698-R, RTI2018-099877-B-I00, CTQ2013-49317-EXP, CTQ2013-41339-P, CTQ2016-75870-P, CTQ2015-71896-REDT (Red de Fotoquímica Biológica) and Instituto de Salud Carlos III (ISCIII; RETIC ARADYAL D16/0006/0012), Junta de Andalucía (PI0250-2016 and UMA18-FEDERJA-007), Orfeo-cinqa network CTQ2016-81797-REDC; the Xunta de Galicia (2015-CP082, ED431C 2017/19, Centro Singular de investigación de Galicia accreditation 2019–2022, ED431G 2019/03), the European Union (European Regional Development Fund - ERDF), and the European Research Council (Advanced Grant No. 340055) are gratefully acknowledged. M.E.V. also acknowledges the support provided by the Fundación AECC IDEAS197VAZQ grant). A.S. was supported by the Uehara Memorial Foundation and a JSPS Postdoctoral Fellowship for Research Abroad.
نبذة مختصرة : MitoBlue is a fluorescent bisamidine that can be used to easily monitor the changes in mitochondrial degradation processes in different cells and cellular conditions. MitoBlue staining pattern is exceptional among mitochondrial dyes and recombinant fluorescent probes, allowing the dynamic study of mitochondrial recycling in a variety of situations in living cells. MitoBlue is a unique tool for the study of these processes that will allow the detailed characterization of communication between mitochondria and lysosomes. ; Yes
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