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Ventilator-associated pneumonia caused by multidrug-resistant Gram-negative bacteria: understanding nebulization of aminoglycosides and colistin.

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      UCL - SSS/IREC/MEDA - Pôle de médecine aiguë; UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie; UCL - (SLuc) Service de soins intensifs; UCL - (SLuc) Service de médecine physique et de réadaptation motrice
    • بيانات النشر:
      Springer Verlag
    • الموضوع:
      2020
    • Collection:
      DIAL@USL-B (Université Saint-Louis, Bruxelles)
    • نبذة مختصرة :
      The use of nebulized antibiotics for treating ventilatorassociated pneumonia (VAP) caused by multidrugresistant (MDR) Gram-negative bacteria (GNB) increases worldwide. There is a paradox, however, between the large body of experimental evidence supporting the administration of nebulized rather than intravenous aminoglycosides and colistin to treat inoculation pneumonia caused by GNB [1, 2], and the paucity of clinical studies confirming such a benefit in VAP. Based on the recommendations of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) [3, 4], the present article examines this apparent contradiction and suggests some directions for further research and clinical practice. [.]
    • ISSN:
      0342-4642
      1432-1238
    • Relation:
      boreal:241983; http://hdl.handle.net/2078.1/241983; info:pmid/31915838; urn:ISSN:0342-4642; urn:EISSN:1432-1238
    • الرقم المعرف:
      10.1007/s00134-019-05890-w
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.5C014B86