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Hepatitis B and C in Europe: an update from the Global Burden of Disease Study 2019

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  • معلومة اضافية
    • Contributors:
      P.A. Cortesi; C. Fornari; S. Conti; I.C. Antonazzo; P. Ferrara; A. Ahmed; C.L. Andrei; T. Andrei; A.A. Artamonov; M. Banach; C.M. Baravelli; T.W. Bärnighausen; A.S. Bhagavathula; N.I. Briko; D. Calina; G. Carrera; S. Chung; M. Dianatinasab; E. Dubljanin; O.C. Durojaiye; I.J. Ezeonwumelu; A.F. Fagbamigbe; F. Fischer; S. Gallu; E.V. Glushkova; D. Golinelli; G. Gorini; S. Hassan; S.I. Hay; M. Hostiuc; I.M. Ilic; M.D. Ilic; M. Jakovljevic; E. Jamshidi; J.J. Jozwiak; Z. Kabir; J.H. Kauppila; R. Khalilov; M.A. Khan; K. Khatab; A. Koyanagi; C. La Vecchia; J.V. Lazaru; C. Ledda; M. Levi; P.D. Lopukhov; J.A. Loureiro; P.C. Matthew; A.A. Menti; T. Mestrovic; B. Moazen; S. Mohammed; L. Monasta; F. Mulita; C.J.L. Murray; I. Negoi; B. Oancea; C. Palladino; J. Patel; I. Petcu; M.J. Postma; D.L. Rawaf; S. Rawaf; E. Romero-Rodríguez; M.M. Santric-Milicevic; V.Y. Skryabin; A.A. Skryabina; R. Tabarés-Seisdedo; M. Tampa; N. Taveira; A. Thiyagarajan; M.R. Tovani-Palone; R. Westerman; M.S. Zastrozhin; G. Mazzaglia; L.G. Mantovani
    • بيانات النشر:
      Elsevier
    • الموضوع:
      2023
    • Collection:
      The University of Milan: Archivio Istituzionale della Ricerca (AIR)
    • نبذة مختصرة :
      Background: In 2016, the World Health Assembly adopted the resolution to eliminate viral hepatitis by 2030. This study aims to provide an overview of the burdens of hepatitis B virus (HBV) and hepatitis C virus (HCV) in Europe and their changes from 2010 to 2019 using estimates from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Methods: We used GBD 2019 estimates of the burden associated with HBV-related and HCV-related diseases: acute hepatitis, cirrhosis and other chronic liver diseases, and liver cancer. We report total numbers and age-standardised rates per 100 000 for mortality, prevalence, incidence, and disability-adjusted life-years (DALYs) from 2010 to 2019. For each HBV-related and HCV-related disease and each measure, we analysed temporal changes and percentage changes for the 2010-19 period. Findings: In 2019, across all age groups, there were an estimated 2·08 million (95% uncertainty interval [UI] 1·66 to 2·54) incident cases of acute hepatitis B and 0·49 million (0·42 to 0·57) of hepatitis C in Europe. There were an estimated 8·24 million (7·56 to 8·88) prevalent cases of HBV-related cirrhosis and 11·87 million (9·77 to 14·41) of HCV-related cirrhosis, with 24·92 thousand (19·86 to 31·03) deaths due to HBV-related cirrhosis and 36·89 thousand (29·94 to 45·56) deaths due to HCV-related cirrhosis. Deaths were estimated at 9·00 thousand (6·88 to 11·62) due to HBV-related liver cancer and 23·07 thousand (18·95 to 27·31) due to HCV-related liver cancer. Between 2010 and 2019, the age-standardised incidence rate of acute hepatitis B decreased (-22·14% [95% UI -35·44 to -5·98]) as did its age-standardised mortality rate (-33·27% [-43·03 to -25·49]); the age-standardised prevalence rate (-20·60% [-22·09 to -19·10]) and mortality rate (-33·19% [-37·82 to -28·13]) of HBV-related cirrhosis also decreased in this time period. The age-standardised incidence rate of acute hepatitis C decreased by 3·24% (1·17 to 5·02) and its age-standardised mortality rate decreased by 35·73% ...
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/37633679; info:eu-repo/semantics/altIdentifier/wos/WOS:001163692200001; volume:8; issue:9; firstpage:e701; lastpage:e716; numberofpages:16; journal:THE LANCET PUBLIC HEALTH; https://hdl.handle.net/2434/994953; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85168736906
    • الرقم المعرف:
      10.1016/S2468-2667(23)00149-4
    • الدخول الالكتروني :
      https://hdl.handle.net/2434/994953
      https://doi.org/10.1016/S2468-2667(23)00149-4
    • Rights:
      info:eu-repo/semantics/openAccess
    • الرقم المعرف:
      edsbas.5B609FE2