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Safety, tolerability, and immunogenicity of inactivated poliovirus vaccine with or without E.coli double mutant heat-labile toxin (dmLT) adjuvant in healthy adults; a phase 1 randomized study.

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • الموضوع:
      2023
    • Collection:
      DI-fusion : dépôt institutionnel de l'Université libre de Bruxelles (ULB)
    • نبذة مختصرة :
      Inactivated trivalent poliovirus vaccine (IPV) induces humoral immunity, which protects against paralytic poliomyelitis but does not induce sufficient mucosal immunity to block intestinal infection. We assessed the intestinal immunity in healthy adults in Belgium conferred by a co-formulation of IPV with the mucosal adjuvant double mutant Labile Toxin (dmLT) derived from Escherichia coli. ; SCOPUS: ar.j ; info:eu-repo/semantics/published
    • File Description:
      1 full-text file(s): application/pdf
    • ISBN:
      978-85-14-73507-6
      85-14-73507-1
    • Relation:
      uri/info:doi/10.1016/j.vaccine.2023.01.048; uri/info:pii/S0264-410X(23)00078-6; uri/info:pmid/36746739; uri/info:scp/85147350719; uri/info:pmcid/PMC9996288; https://dipot.ulb.ac.be/dspace/bitstream/2013/357918/1/doi_341562.pdf; http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/357918
    • الدخول الالكتروني :
      http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/357918
      https://dipot.ulb.ac.be/dspace/bitstream/2013/357918/1/doi_341562.pdf
    • الرقم المعرف:
      edsbas.501B4DA1