نبذة مختصرة : In this work, to improve antibacterial, biocompatible and bioactive properties of commercial pure titanium (cp-Ti) for implant applications, the Zn-deposited nanotube surfaces were fabricated on cp-Ti by using combined anodic oxidation (AO) and physical vapor deposition (PVD-TE) methods. Homogenous elemental distributions were observed through all surfaces. Moreover, Zn-deposited surfaces exhibited hydrophobic character while bare Ti surfaces were hydrophilic. Due to the biodegradable behavior of Zn on the nanotube surface, Zn-deposited nanotube surfaces showed higher corrosion current density than bare cp-Ti surface in SBF conditions as expected. In vitro biological properties such as cell viability, ALP activity, protein adsorption, hemolytic activity and antibacterial activity for Gram-positive and Gram-negative bacteria of all surfaces were investigated in detail. Cell viability, ALP activity and antibacterial properties of Zn-deposited nanotube surfaces were significantly improved with respect to bare cp-Ti. Moreover, hemolytic activity and protein adsorption of Zn-deposited nanotube surfaces were decreased. According to these results; a bioactive, biocompatible and antibacterial Zn-deposited nanotube surfaces produced on cp-Ti by using combined AO and PVD techniques can have potential for orthopedic and dental implant applications.
Relation: Scientific Reports; info:eu-repo/grantAgreement/TUBITAK/SOBAG/118M766; Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı; Durdu, S., Cihan, G., Yalçın, E., Çavuşoğlu, K., Altınkök, A., Sağcan, H. . Usta, M. (2023). Surface characterization, electrochemical properties and in vitro biological properties of Zn-deposited TiO2 nanotube surfaces. Scientific Reports, 13(1). https://dx.doi.org/10.1038/s41598-023-38733-2; https://dx.doi.org/10.1038/s41598-023-38733-2; https://hdl.handle.net/20.500.12511/11275; 13; Q2; 001030642400017; 2-s2.0-85164755730; Q1
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