The Analysis of the Association of the MAOA Gene Polymorphism with Aggressive and Hostile Behaviour Strategies in Adolescents and Young People ; Анализ ассоциаций полиморфизма гена МАОА с агрессивными и враждебными стратегиями в поведении у подростков и молодых людей

The article brings forward the results of the study of the relationship betweenpolymorphisms of the MAOA gene and psychological characteristics such as hostilityand types of aggressive behavior. Aggression is considered as any intentionalactions aimed at causing harm to another person, group of people or animal.The authors of the article mean by hostility a negative, opposition attitude to theworld; it is predominantly of a cognitive nature and presupposes the presence ofnegative emotions and behavioral manifestations.This paper describes various psychophysiological predictors of aggressivebehavior and examines the results of domestic and foreign research of therelationship between polymorphic variants of the MAOA gene with variouspsychological characteristics.The authors carried out an interdisciplinary molecular-genetic and psychologicalstudy. 285 persons aged 12–19 years took part in it. In order to identify polymorphicvariants of the MAOA gene they used the method for the isolation of genomicDNA from buccal epithelial cells. Psychological tools included the questionnaireBass–Darky which is reckoned one of the most reliable methods for studyingaggression. For statistical processing of the results the PSPP 0.8.5 program wasused.The results of the carried out study in the group of adolescents and youngpeople show that the low-activity variant of the monoamine oxidase A (MAOA)gene (LPR) in adolescents and young people is the most signiYcant among thegenetic polymorphisms which determine the risk of aggressive and hostile behavior.The data should be taken into account in psycho-preventive activities. ; В статье представлены результаты исследования, посвященного изучению связи полиморфизмов гена МАОА с такими психологическими особенностями, как враждебность и виды агрессивного поведения. Агрессия рассматривается как любые намеренные действия, которые направлены на причинение ущерба другому человеку, группе людей или животному. Под враждебностью в статье понимается негативное, оппозиционное отношение к окружающему ...