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Prediction of Trimethoprim/Sulfamethoxazole Resistance in Community-Onset Urinary Tract Infections

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • بيانات النشر:
      Scholar Commons
    • الموضوع:
      2020
    • Collection:
      University of South Carolina Libraries: Scholar Commons
    • نبذة مختصرة :
      OBJECTIVES: This study aimed to predict trimethoprim/sulfamethoxazole (SXT) resistance in patients with community-onset urinary tract infection (UTI) due to Enterobacteriaceae based on patient-specific risk factors. METHODS: This was a retrospective case-control study in Prisma Health facilities in central South Carolina, USA, including three community hospitals, affiliated emergency departments and ambulatory clinics, including adult patients with community-onset UTI due to Enterobacteriaceae (1 April 2015 to 29 February 2016). Multivariate logistic regression was used to examine risk factors for SXT resistance. RESULTS: Among 351 unique patients with community-onset UTI, 71 (20.2%) had SXT-resistant Enterobacteriaceae urinary isolates. Overall, median age was 64 years and 252 (71.8%) were female. A multivariate model identified prior urinary infection/colonisation with SXT-resistant Enterobacteriaceae (OR=8.58, 95% CI 3.92-18.81; P
    • File Description:
      application/pdf
    • Relation:
      https://scholarcommons.sc.edu/phar_facpub/49; https://scholarcommons.sc.edu/context/phar_facpub/article/1048/viewcontent/1_s2.0_S2213716519302851_main.pdf
    • الرقم المعرف:
      10.1016/j.jgar.2019.10.023;
    • الدخول الالكتروني :
      https://scholarcommons.sc.edu/phar_facpub/49
      https://doi.org/10.1016/j.jgar.2019.10.023;
      https://scholarcommons.sc.edu/context/phar_facpub/article/1048/viewcontent/1_s2.0_S2213716519302851_main.pdf
    • Rights:
      http://dx.doi.org/10.1016/j.jgar.2019.10.023 2213-7165/© 2019 International Society for Antimicrobial Chemotherapy. Published by Elsevier Ltd. This is an open access article under the CC BY-NC-ND license ( http:// creativecommons.org/licenses/by-nc-nd/4.0/ ).
    • الرقم المعرف:
      edsbas.48FB4044