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Preclinical Retinal Neurodegeneration in a Model of Multiple Sclerosis

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  • المؤلفون: Deepali Mathur; Alberto Hernandez Cano
  • المصدر:
    Annals of Neurosciences; Vol 19, No 3 (2012): Annals of Neurosciences
  • نوع التسجيلة:
    other/unknown material
  • اللغة:
    unknown
  • معلومة اضافية
    • بيانات النشر:
      Annals of Neurosciences
    • الموضوع:
      2012
    • Collection:
      Annals of Neurosciences (Indian Academy Of Neurosciences)
    • نبذة مختصرة :
      Ever since the pathology of multiple sclerosis (MS) was described, it has been debated whether immune-mediated myelin damage is a primary or secondary event to axon degeneration. Traditionally the disease is considered to ensue as a consequence of demyelination followed by neuronal loss. Recent in vivo findings, however, demonstrate axons to be the primary target of the disease process. Animal models of MS are greatly instrumental in studying the pathogenesis of the disease and understanding the sequence of events that take place in neurodegenerative disorders. DOI:10.5214/ans.0972.7531.190307
    • File Description:
      application/pdf; text/html; text/xml
    • Relation:
      http://annalsofneurosciences.org/journal/index.php/annal/article/view/451
    • الدخول الالكتروني :
      http://annalsofneurosciences.org/journal/index.php/annal/article/view/451
    • Rights:
      The corresponding author should agree, by the act of submission, that the copyright of the manuscript, was in fact transferred to the journal and would be done so without any renumeration from the Journal, such transfer being irrevocable after publication. Authors hold the right to withdraw any manuscript from consideration for publication for any reason until the issue was copyset for publication, after which the manuscripts would be retracted. On behalf of all authors the submitting author should either be the corresponding author or if not, the corresponding author should assert by submission of any and all manuscripts for review that the manuscript is not under consideration elsewhere. That all individuals who participated in the study in a material manner are listed as authors, or if not, why. That all authors have reviewed and agree with the content, presentation, organization, data and interpretation of the data or the manuscript as well as their position within the authorship list, that no individual who either holds or claims any authorship right has been excluded and if not, explain, that the facts of the paper are true and honest and that all experiments that require institutional or governmental approval have been submitted, evaluated and awarded required approvals including but not limited to human experimentation and clinical trials, animal use, use of toxic chemicals and radioactive elements, regulators pertaining to any and all aspects of ICMR-DBT guidelines of stem cell research if applicable, or any other regulation pertinent to the study. On behalf of all authors, the corresponding author agrees to be listed as such, and all other authors consent to this listing. The listed corresponding author on behalf of all authors by submission of the paper for review or publication testifies that he or she is reasonably certain that the data presented are accurate, has no reason to question the validity of any fact, statement or experimental result presented in the paper, has directly participated in all aspects of the study has not copied the work or any aspect of it from another source, has not reviewed any paper that presents substantially identical results and has in fact not accepted that paper for publication or is aware that the paper is no longer being evaluated for publication unless that paper is referred to by reference of footnote in the submitted manuscript, that any and all future allegations of scientific misconduct or fraud that arise from either the submission or publication of the paper shall be relayed to the editor in chief in timely manner and that the proceedings of any investigation will be communicated as they evolve, that the journal reserves the right to publish such information if that information is in fact in the public domain and to comment upon it as the findings if invalid relate to the science communicated by the Journal.
    • الرقم المعرف:
      edsbas.48D3440B