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A novel signaling pathway mediated by the nuclear targeting of C-terminal fragments of mammalian Patched 1.

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  • معلومة اضافية
    • بيانات النشر:
      PloS
    • Collection:
      Hokkaido University Collection of Scholarly and Academic Papers (HUSCAP) / 北海道大学学術成果コレクション
    • الموضوع:
      499
    • نبذة مختصرة :
      Patched 1 (Ptc1) is a polytopic receptor protein that is essential for growth and differentiation. Its extracellular domains accept its ligand, Sonic Hedgehog, while the function of its C-terminal intracellular domain is largely obscure.
    • Relation:
      http://hdl.handle.net/2115/53698; PloS one, 6(4): e18638; http://dx.doi.org/10.1371/journal.pone.0018638
    • الرقم المعرف:
      10.1371/journal.pone.0018638
    • Rights:
      http://creativecommons.org/licenses/by/3.0/
    • الرقم المعرف:
      edsbas.458478A8