نبذة مختصرة : Bu tezin, veri tabanı üzerinden yayınlanma izni bulunmamaktadır. Yayınlanma izni olmayan tezlerin basılı kopyalarına Üniversite kütüphaneniz aracılığıyla (TÜBESS üzerinden) erişebilirsiniz. ; 8. ROSACEA: FACTORS AFFECTING THE COURSE AND OCULAR INVOLVEMENT Rosacea is a dermatose occuring in the central region of the face characterized by episodic flushing, erythema, telengiectasia, papules and papulopustules. The incidence of ocular signs and symptoms in rosacea were detected to be variable in different series. In this study demographic, clinical features and provoking factors in 50 patients with rosacea were investigated. In addition the ocular signs and symptoms were evaluated in 32 of them. The rosacea patients underwent testing of tear break-up time, Schirmer testing and rose Bengal staining and the results were compared with that of 15 controls. Rosacea was detected to be more common in women, and the severity of the disease were not significantly different regarding gender. The lesions were found to be symmetrically distrubuted, the cheek being the most affected region. More than 50% of the patients reported an increase in symptoms with sun exposure, stress and soaps. All patients showed signs and symptoms of ocular disease. The most frequent ocular symptoms were itching, burning and photosensitivity, and the most frequent ocular signs were blepharitis, meibomitis, and telengiectasia. The stage of cutaneous rosacea showed a positive correlation with the number of ocular signs. The difference between flushing and the number of ocular signs and symptoms were not statistically significant. The mean tear break-up time of the patients and the controls were 10,00 and 13,27 seconds respectively. This difference was found to be statistically significant The Schirmer test showed an average of 11,56mm of wetting with rosacea, while the controls had an average of 14,27mm of wetting and the difference was statistically significant Rose Bengal staining scores were higher in rosacea patients than controls. In conclusion, ...
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