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Early experimental COVID-19 therapies: associations with length of hospital stay, mortality and related costs

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المؤلفون: Vernaz-Hegi, Nathalie; Agoritsas, Thomas; Calmy, Alexandra; Gayet-Ageron, Angèle; Gold, Gabriel; Perrier, Arnaud; Picard, Fabienne; Prendki, Virginie; Reny, Jean-Luc; Samer, Caroline Flora; Stirnemann, Jérôme; Vetter, Pauline; Zanella, Marie-Céline; Zekry Berger, Dina Selma; Baggio, Stéphanie
المصدر:
ISSN: 1424-7860 ; Swiss Medical Weekly, vol. 150 (2020) w20446.
الموضوع:
info:eu-repo/classification/ddc/613; info:eu-repo/classification/ddc/616; info:eu-repo/classification/ddc/616.8; info:eu-repo/classification/ddc/617; info:eu-repo/classification/ddc/618; info:eu-repo/classification/ddc/618.97; Adolescent; Adult; Age Factors; Aged; 80 and over; Antiviral Agents/administration & dosage/adverse effects/therapeutic use; COVID-19/drug therapy/epidemiology/mortality; Child; Preschool; Comorbidity; Drug Combinations; Drug Therapy; Combination; Health Expenditures; Hospital Mortality/trends; Humans; Hydroxychloroquine/administration & dosage/adverse effects/therapeutic use; Infant; Length of Stay/statistics & numerical data; Lopinavir/administration & dosage/adverse effects/therapeutic use; Middle Aged; Pandemics; Retrospective Studies; Ritonavir/administration & dosage/adverse effects/therapeutic use
نوع التسجيلة:
article in journal/newspaper
اللغة:
English

معلومة اضافية
- الموضوع:
  2020
- Collection:
  Université de Genève: Archive ouverte UNIGE
- نبذة مختصرة :
  Hydroxychloroquine and lopinavir/ritonavir have been used as experimental therapies to treat COVID-19 during the first wave of the pandemic. Randomised controlled trials have recently shown that there are no meaningful benefits of these two therapies in hospitalised patients. Uncertainty remains regarding the potential harmful impact of these therapies as very early treatments and their burden to the health care system. The present study investigated the length of hospital stay (LOS), mortality, and costs of hydroxychloroquine, lopinavir/ritonavir or their combination in comparison with standard of care among patients hospitalised for coronavirus disease 2019 (COVID-19).
- Relation:
  info:eu-repo/semantics/altIdentifier/pmid/33382449; https://archive-ouverte.unige.ch/unige:151585; unige:151585
- Rights:
  info:eu-repo/semantics/openAccess
- الرقم المعرف:
  edsbas.40471E0

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