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Inulin-type fructan associated with cafeteria diet: effect on the cardiometabolic profile of Wistar rats ; Frutanos tipo inulina associados à dieta de cafeteria: efeito no perfil cardiometabólico de ratos Wistar

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  • معلومة اضافية
    • بيانات النشر:
      Universidade Estadual de Londrina
    • الموضوع:
      2019
    • Collection:
      Universidade Estadual de Londrina: Portal de Periódicos Científicos da UEL
    • نبذة مختصرة :
      The cafeteria diet was developed in order to mimic the western diet, since it is associated with disorders in the cardiovascular profile, such as dyslipidemia, hyperglycemia, accumulation of body fat, among others. Inulin-type fructan (ITF) are soluble fibers categorized as prebiotics. The present study aimed to evaluate the effects of ITF associated with cafeteria diet on the cardiometabolic profile in Wistar rats. For this, 30 animals were used. The purified ITFs, as well as from the food matrix (yacon powder), were added to their respective experimental groups at a dose of 6% for 30 days. The analyzed variables were: centesimal composition and ITF content, weight gain (WG), relative weight of cecum (RWC), relative liver weight (RLW), dietary intake, glycemia, triglycerides, total cholesterol, HDL-c, LDL -c, subcutaneous and visceral adipose tissue (epididimal, retroperitoneal and mesenteric). All analyzes followed the standardized protocols. Statistical analysis was performed using the Sigma Stat 4.0 software and a Shapiro-Wilk normality test, descriptive tests, ANOVA or Kruskal-Wallis test followed by the Duncan or Dunn’s averages comparison tests were performed. The level of significance was set at p <0.05. The RWC variable was statistically higher in the groups submitted to FTI. The group that received a cafeteria diet presented higher values in WG, VLDL, triglycerides, subcutaneous and epididimal adipose tissue. There was no statistical difference in the parameters RLW, total cholesterol, LDL-c, HDL-c and glycemia. Therefore, through this work, beneficial systemic effects of ITF were observed in parameters such as: RWC, WG, VLDL, triglycerides and adipose tissue. ; A dieta de cafeteria foi desenvolvida a fim de mimetizar a dieta ocidentalizada, uma vez que esta associa-se a desordens no perfil cardiovascular, como dislipidemias, hiperglicemia, acúmulo de gordura corporal, entre outros. Os frutanos tipo inulina (FTI) são fibras solúveis categorizados como prebióticos. O presente estudo objetivou avaliar ...
    • File Description:
      application/pdf
    • Relation:
      https://ojs.uel.br/revistas/uel/index.php/seminabio/article/view/33058/26012; https://ojs.uel.br/revistas/uel/index.php/seminabio/article/view/33058
    • الرقم المعرف:
      10.5433/1679-0367.2019v40n1p25
    • الدخول الالكتروني :
      https://ojs.uel.br/revistas/uel/index.php/seminabio/article/view/33058
      https://doi.org/10.5433/1679-0367.2019v40n1p25
    • Rights:
      Copyright (c) 2019 Semina: Ciências Biológicas e da Saúde ; http://creativecommons.org/licenses/by-nc/4.0
    • الرقم المعرف:
      edsbas.3FA7FB57