Contributors: Institut des Sciences Chimiques de Rennes (ISCR); Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes); Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie - CNRS Chimie (INC-CNRS)-Centre National de la Recherche Scientifique (CNRS); University College of London London (UCL); Cardiff University; We are grateful to the CNRS, the Ecole Nationale Supérieure de Chimie de Rennes, the University College London and the Cardiff University. The authors gratefully acknowledge financial support by the Region Bretagne (ARED 2018 “Biometa” N°601, grant to J.M.), the Agence Nationale de la Recherche (ANR-19-CE07-0017 “ChiCAAC” and ANR-20-CE07-0030 “c-Résolu”), DEMETA SAS and “France relance” (for fellowship to A.D.V.), UCL (for a studentship to H.R.S.), Cardiff University and EPSRC (for a stu-dentship to T.M. EP/N509449/1).; ANR-19-CE07-0017,ChiCAAC,Carbènes alkyl amino cycliques chiraux en catalyse asymétrique(2019); ANR-20-CE07-0030,cResolu,Accès direct à des complexes chiraux NHC-métal de transition : de nouvelles opportunités pour la catalyse asymétrique(2020)
نبذة مختصرة : International audience ; The versatility of olefin metathesis is evident from its successful applications ranging from natural product synthesis to the valorization of renewable feedstocks. On the other side, flow chemistry has recently gained particular interest among the synthetic community, offering valuable alternatives to classic batch chemistry and paving the way to the development of new transformations. The application of continuous flow to olefin metathesis represents one of the most promising evolutions in the field at the interface of industrially relevant synthesis and reactor engineering, significantly improving some of the typical problems such as undesired self-reactions and ethylene-mediated catalyst de-activation. This review aims to provide a small survey covering the major aspects of those techniques which we hope may be of interest for the chemical community, but also those interested in catalysis, continuous processing, enabling technologies and reactor design.
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