نبذة مختصرة : Background : There were estimated 0.5 to 10 cases per 100,000 people suffering from thyroid nodules. Malignant thyroid nodules that require immediate treatment, whereas benign could be therapeutically treated. FNAB is the initial diagnostic step of thyroid nodules. FNAB technique is safe, inexpensive, reliable and has minor risk of complications.Objective : To describe the diagnostic value of FNAB compared with histopathological biopsy in the diagnosis of thyroid carcinoma in RSUP Dr. Kariadi SemarangMethod : The study subjects were patients in RSUP Dr. Kariadi Semarang who had thyroid nodules and had been examined using FNAB and histopathological biopsy. Data of FNAB and histopathological biopsy examination of each sample were collected to calculate sensitivity, specificity, positive predicted value, and negative predicted value.Result : There were 34 samples obtained. Sensitivity, specificity, positive predicted value, and negative predicted value of FNAB were 100%, 84%, 69,2%; and 100% respectively.Conslusion : FNAB has a good diagnostic value to diagnose thyroid carcinoma.
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