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Characteristics of human and viral RNA binding sites and site clusters recognized by SRSF1 and RNPS1

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  • معلومة اضافية
    • الموضوع:
      2020
    • Collection:
      Zenodo
    • نبذة مختصرة :
      This dataset was developed for the following article: Rogan PK, Mucaki EJ and Shirley BC. A proposed molecular mechanism for pathogenesis of severe RNA-viral pulmonary infections [version 1; peer review: awaiting peer review]. F1000Research 2020, 9:943 (https://doi.org/10.12688/f1000research.25390.1) Section 1. Extended Data Tables This archive contains the extended data tables for the research article "A proposed mechanism for molecular pathogenesis of severe RNA-viral pulmonary infections". These tables provide SRSF1, RNPS1 and hnRNP A1 binding site and information-dense cluster counts across various RNA viral genomes [including multiple SARS-CoV-2 and influenza strains] and the human transcriptome, the estimated SARS-CoV-2 doubling time necessary for viral genome SRSF1 binding site availability to exceed sites within the host transcriptome, and an analysis of influenza, dengue, and aplastic anemia patients misdiagnosed as irradiated by established radiation gene signatures.These tables are: Section 1 - Table 1. RNPS1 and hnRNPA1 binding sites and Information-Dense Clusters for RNPS1 and hnRNPA1 in RNA Virus Genomes Section 1 - Table 2A. Detailed Analysis of Information-Dense Clusters for SRSF1 (Replicate 1) in RNA Virus Genomes Section 1 - Table 2B. Detailed Analysis of Information-Dense Clusters for SRSF1 (Replicate 2) in RNA Virus Genomes Section 1 - Table 2C. Detailed Analysis of Information-Dense Clusters for RNPS1 in RNA Virus Genomes Section 1 - Table 2D. Detailed Analysis of Information-Dense Clusters for hnRNP A1 in RNA Virus Genomes Section 1 - Table 3. Binding Site Analysis of Multiple Coronavirus Strains (Both Strands) Section 1 - Table 4A. Binding Site Analysis of Multiple Influenza A (H3N2) Strains (Negative Strand Only) Section 1 - Table 4B. Binding Site Analysis of Multiple Influenza A (H3N2) Strains (Both Strands) Section 1 - Table 5. SRSF1, RNPS1 and hnRNPA1 Binding Sites and Information-Dense Clusters by Gene Section 1 - Table 6A. Transcriptome-Wide Information Dense Clusters Intersecting ...
    • Relation:
      https://zenodo.org/communities/covid-19; https://zenodo.org/communities/zenodo; https://zenodo.org/record/4315165; https://doi.org/10.5281/zenodo.4315165; oai:zenodo.org:4315165
    • الرقم المعرف:
      10.5281/zenodo.4315165
    • Rights:
      info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by/4.0/legalcode
    • الرقم المعرف:
      edsbas.2F23B614