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Experimental Assessment of Physician Modified Proximal Scalloped Stent Graft to Extend Proximal Landing Zone in the Aortic Arch

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  • معلومة اضافية
    • Contributors:
      Physiologie & médecine expérimentale du Cœur et des Muscles U 1046 (PhyMedExp); Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS); Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier); Service de chirurgie thoracique et cardio-vasculaire; Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Hôpital Arnaud de Villeneuve CHRU Montpellier; Centre Hospitalier Régional Universitaire Montpellier (CHRU Montpellier)-Université de Montpellier (UM)
    • بيانات النشر:
      HAL CCSD
      Elsevier
    • الموضوع:
      2017
    • Collection:
      Université de Montpellier: HAL
    • نبذة مختصرة :
      International audience ; Objective/Background: The aim of the study was to assess a model of physician modified scalloped stent graft (PMSG) on currently available thoracic aortic devices to extend the proximal landing zone in either zone 2, 1 or 0 of the aortic arch while preserving flow in the supra-aortic vessels on human cadaveric aorta.Methods: Fresh human aortas were harvested at autopsy from adult subjects. A proximal scallop was made on the stent grafts based on direct measurements on the aortas to extend the proximal landing zone in zone 0 (n ¼ 5), zone 1 (n ¼ 5), and zone 2 (n ¼ 5). A previously described benchtop closed system pulsatile flow model was used to mimic flow and pressure conditions in the aorta to deploy the stent graft as close to physiological conditions as possible. Deployment accuracy of the scallop opposite the aortic arch branch ostia was assessed by completion angiography and post-procedural analysis of the aortas.Results: Fifteen proximal scalloped stent grafts were deployed in the aortic arch of 15 human cadaveric aortas under fluoroscopy. The expected proximal landing zone was achieved in all cases (zone 2 ¼ 5; zone 1 ¼ 5; zone 0 ¼ 5). Post-procedural angiography and direct visual analysis showed supra-aortic vessel patency and deployment of the scallop opposite the aortic arch branch ostia in all cases.Conclusion: PMSG to extend the proximal landing zone in zone 2, 1, or 0 in order to treat urgent diseases of the proximal descending aorta or the inner circumference of the aortic arch by a totally endovascular approach while preserving flow in the supra-aortic trunks is experimentally feasible. Ó
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/28615114; hal-01760707; https://hal.science/hal-01760707; https://hal.science/hal-01760707/document; https://hal.science/hal-01760707/file/2017%20Faure%20et%20al.,%20Experimental%20%20assessment.pdf; PUBMED: 28615114
    • الرقم المعرف:
      10.1016/j.ejvs.2017.04.019
    • الدخول الالكتروني :
      https://hal.science/hal-01760707
      https://hal.science/hal-01760707/document
      https://hal.science/hal-01760707/file/2017%20Faure%20et%20al.,%20Experimental%20%20assessment.pdf
      https://doi.org/10.1016/j.ejvs.2017.04.019
    • Rights:
      info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.2C2BBE42