Additional file 1 of COVID-19 and risk of subsequent life-threatening secondary infections: a matched cohort study in UK Biobank

Additional file 1: Figures S1-S4 and Tables S1-S5. Figure S1. Flow chart for the ascertainment of exposure and outcome diseases. Figure S2. Comparison of the hazards of life-threatening secondary infections in COVID-19 and seasonal influenza patients in the sensitivity analyses where the maximum follow-up time was set as 1 month. Figure S3. Comparison of the hazards of life-threatening secondary infections in COVID-19 and seasonal influenza patients in the sensitivity analyses where no limit was set to the maximum follow-up. Figure S4. Comparison of the hazards of bacteria sepsis in COVID-19 and seasonal influenza matched cohorts. Table S1. SNOMED CT codes used to ascertain seasonal influenza in primary care data (EMIS GP system) with mapping to 3-digits ICD-10 codes. Table S2. CTV3 codes used to ascertain seasonal influenza in primary care data (TPP GP system) with mapping to 3-digits ICD-10 codes. Table S3. ICD-10 codes used to ascertain major life-threatening infections. Table S4. ICD-10 coding algorithms for Charlson comorbidity index calculation. Table S5. Distribution of the underlying pathogens for sepsis cases among COVID-19/seasonal influenza patients and their matched individuals.