Clinical evaluation of universal adhesives used with different application modes on the restoration of non-carious cervical lesions: preliminary findings of a 12-month randomized, controlled clinical trial

Objective: To evaluate the performances of two different universal adhesives applied with different modes and an etch&rinse adhesive for the restoration of non-carious cervical lesions. Materials and Method: Twenty patients received 155 restorations. The lesions were divided into 7 groups based on the adhesive systems and application modes: GSE: Gluma Universal/self-etch, GSL: Gluma Universal/selective-etching, GER: Gluma Universal/etch&rinse, ASE: All Bond Universal/self etch, ASL: All Bond Universal/selective-etching, AER: All Bond Universal/etch&rinse, SB (Control): Single Bond 2/etch&rinse. A nano-hybrid composite resin was used for the restorations. Then, the restorations were scored according to USPHS criteria after a week, 6- and 12-months. The data were statistically analyzed using Chi-square, Cochrane Q and McNemar’s tests (α=0.05). Results: On the 6th month of the evaluation three restorations from each of the GSE and ASE groups lost retention, and on the 12th month of the evaluation cumulative retention loss rate was 23.8% for the GSE and 20% for the ASE groups (p<0.05, more restoration loss in these groups were seen compared to the other groups). On the 6th and 12th month of the evaluations, no statistically significant differences were found among the groups for marginal adaptation, marginal discoloration, secondary caries and post-operative sensitivity (p>0.05). Regarding the intra-group comparisons, compared to the baseline, a significant retention loss was seen in the ASE and GSE groups as early as 6-months; and significant marginal adaptation loss and marginal discoloration was detected in all groups on the 12th month (p<0.05). Conclusion: Regarding the retention on the 12th month, Gluma Universal and All-Bond Universal applied with the etch&rinse and selective-etching modes were similar to the control, and showed better results than those applied with the self-etch mode. Marginal adaptation, marginal discoloration, post-operative sensitivity and secondary caries ...