Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Seroprevalence study in humans and molecular detection in Rhipicephalus sanguineus ticks of severe fever with thrombocytopenia syndrome virus in Thailand

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
  • معلومة اضافية
    • Contributors:
      Mahidol University Bangkok; Suan Sunandha Rajabhat University; Unité des Virus Emergents (UVE); Institut de Recherche pour le Développement (IRD)-Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM); Phon Phisai Hospital; Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC); Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD Occitanie )-Université de Montpellier (UM); This work was financially supported by the Office of the Permanent Secretary, Ministry of Higher Education, Science, Research and Innovation (OPS MHESI), Thailand Science Research and Innovation (TSRI) (Grant No.RGNS 64-172) and international postdoctoral fellowship 2022 provided by Mahidol University
    • بيانات النشر:
      HAL CCSD
      Nature Publishing Group
    • الموضوع:
      2024
    • Collection:
      Université de Montpellier: HAL
    • نبذة مختصرة :
      International audience ; Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne virus with a mortality rate of up to 30%. First identified in China in 2009, it was later reported in other Asian countries, including Thailand in 2020. SFTSV has been detected in several tick species, including Rhipicephalus sanguineus , known for infesting dogs. We conducted a seroprevalence study of SFTSV in Bangkok and Nong Khai, Thailand, by analyzing 1162 human samples collected between 2019 and 2023. The testing method relied on IgG detection using ELISA and confirmed though a virus seroneutralization test. The results indicated that out of the participants, 12 (1.1%) tested positive for anti-SFTSV IgG antibodies; however, none exhibited positive results in the seroneutralization assay. Additionally, molecular detection of SFTSV, Crimean-Congo hemorrhagic fever (CCHF), Coxiella spp., Bartonella spp., and Rickettsia spp. was performed on 433 Rh. sanguineus ticks collected from 49 dogs in 2023 in Chachoengsao Province, Thailand. No evidence of these pathogens was found in ticks. These findings highlight the importance of exploring viral cross-reactivity. Furthermore, it is important to conduct additional studies to isolate SFTSV from animals and ticks in order to identify the potential transmission routes contributing to human and animal infections in Thailand.
    • Relation:
      info:eu-repo/semantics/altIdentifier/pmid/38862576; PUBMED: 38862576; PUBMEDCENTRAL: PMC11167008
    • الرقم المعرف:
      10.1038/s41598-024-64242-x
    • الدخول الالكتروني :
      https://hal.science/hal-04650805
      https://hal.science/hal-04650805v1/document
      https://hal.science/hal-04650805v1/file/s41598-024-64242-x%20%281%29.pdf
      https://doi.org/10.1038/s41598-024-64242-x
    • Rights:
      http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess
    • الرقم المعرف:
      edsbas.1A2AA2B1