Changes of coagulation function and risk of stroke in patients with COVID‐19

Background and purpose COVID‐19 is spreading throughout the whole world as a public health issue. There is a link between the new coronavirus and changes in biochemical indicators, such as coagulation functions. Hypercoagulable state of blood caused by infections may lead to cerebrovascular diseases. More attention should be paid to patients with COVID‐19, especially critically ill individuals with history of cerebrovascular disease who may have high risk of stroke. Methods 193 patients with COVID‐19 were enrolled in the study. These patients were categorized into nonsevere (143 patients) and severe (50 patients) groups. This study evaluated laboratory tests, including routine blood tests, C‐reactive protein, erythrocyte sedimentation rate, electrolytes, and coagulation functions. Furthermore, neurological function and stroke risks were evaluated in this study. Results Compared to the nonsevere group, there were increases in white blood cells, neutrophil count, interleukin‐6, erythrocyte sedimentation rate, and C‐reactive protein in the severe group (p
The study examined whether there were differences in coagulation functions between critically ill patients with COVID‐19 and nonsevere patients. Whether these changes were associated with neurological function and stroke risks were also examined.