Investigation of the relationship between alopecia areata and inflammatory blood parameters

AIM Alopecia areata (AA) is an inflammatory condition that causes regional shedding without scarring on the hair or eyebrows, eyelashes, and beard. In studies conducted, it has been concluded that platelet/lymphocyte ratio (PLR), neutrophil/lymphocyte ratio (NLR), and mean platelet volume (MPV) are significant indicators of systemic inflammation in various diseases. In the present study, our aim was to examine these parameters in AA patients and to investigate their relationship with the disease. MATERIALS AND METHODS A total of 135 AA patients and 135 healthy controls who did not have any systemic, inflammatory, infectious, or autoimmune diseases were included in this study. Demographic characteristics and complete blood count (CBC) results were analyzed retrospectively and recorded, and statistical analysis was performed. RESULTS PLR, NLR, and MPV values were not differ between AA patients and the control group. CONCLUSION It can be concluded that PLR, NLR, and MPV values are not convenient parameters to show inflammatory response in AA.