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A propensity score-adjusted analysis of efficacy of high-flow nasal oxygen during awake tracheal intubation

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  • معلومة اضافية
    • Contributors:
      Hye Jin Kim; Min-Soo Kim; So Yeon Kim; In Kyung Min; Wyun Kon Park; Sei Han Song; Dongkwan Shin; Hyun Joo Kim; Kim, Min Soo
    • بيانات النشر:
      Springer Science and Business Media LLC, 2022.
    • الموضوع:
      2022
    • نبذة مختصرة :
      Oxygen supplementation is crucial for awake tracheal intubation (ATI) using a flexible bronchoscope in patients with an anticipated difficult airway. However, the modality of optimal oxygen delivery remains unclear. This retrospective study compared high-flow nasal oxygen (HFNO) and conventional low-flow oxygen supply during ATI. We applied inverse probability of treatment weighting (IPTW) to account for biases due to clinical characteristic differences between the groups. The primary endpoint was the lowest oxygen saturation during ATI. The secondary endpoints were incidence of desaturation, multiple attempts, failure rate, and procedural duration. After IPTW adjustment, the lowest oxygen saturation in the HFNO group during ATI was significantly higher than that in the conventional oxygenation group (99.3 ± 0.2 vs. 97.5 ± 0.5, P P = 0.007). There were no significant differences between the two groups in the incidence of desaturation, failure and procedural duration. Our findings suggest that HFNO was associated with improved lowest oxygen saturation and a lower rate of multiple attempts during ATI. Therefore, we recommend using HFNO for safer oxygen delivery and improved quality of procedure during ATI.
    • ISSN:
      2045-2322
    • الرقم المعرف:
      10.1038/s41598-022-15608-6
    • Rights:
      CC BY
      CC BY NC ND
      URL: http://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (http://creativecommons.org/licenses/by/4.0/) .
    • الرقم المعرف:
      edsair.doi.dedup.....db461a50cce03a776c814e269f2d4259