نبذة مختصرة : Background The use of face mask for early treatment of class III malocclusion has proven to be successful, but its compliance and related dental side effects have always been a problem. To overcome this, a new approach has been suggested. The purpose of the present study was to compare the effectiveness of reverse twin block with lip pads and fixed rapid maxillary expansion (RTBLP-RME) appliance and face mask with RME (FM-RME) appliance for early treatment of class III malocclusion. Methods The sample consisted of 39 patients with class III malocclusion in the age group of 6–12 years (mean 10.17). They were divided into 3 groups of 13 each: reverse twin block with lip pads-RME (RTBLP-RME), face mask with RME (FM-RME), and control group. Treatment time was 9 months. Lateral cephalograms were taken at the start of treatment (T1) and after 9 months (T2) (both groups). Results Both appliances were effective in correction of class III malocclusion with significant (p
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