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Maintaining the thyroid gland in mutant thyroglobulin–induced hypothyroidism requires thyroid cell proliferation that must continue in adulthood

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اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • بيانات النشر:
      Elsevier BV, 2022.
    • الموضوع:
      2022
    • نبذة مختصرة :
      Congenital hypothyroidism with biallelic thyroglobulin (Tg protein, encoded by the TG gene) mutation is an endoplasmic reticulum (ER) storage disease. Many patients (and animal models) grow an enlarged thyroid (goiter), yet some do not. In adulthood, hypothyroid TG
    • ISSN:
      0021-9258
    • الرقم المعرف:
      10.1016/j.jbc.2022.102066
    • Rights:
      OPEN
    • الرقم المعرف:
      edsair.doi.dedup.....c638dfe69f0984f083f8ce192c4aa086