Plexiform Schwannoma of the Stomach in Neurofibromatosis Type 2: A Case Report

Plexiform schwannoma is a benign neoplasm of the peripheral nerves. It is generally localized in the skin and subcutaneous tissues of the head, neck, arms, and chest. Visceral localization of plexiform schwannoma is very uncommon (1). In particular, gastric involvement of plexiform schwannoma is extremely rare. Neurofibromatosis type 2 (NF2) is a dominantly inherited tumor-prone disorder characterized by the development of multiple schwannoma and meningiomas (2). The clinical features of NF2 typically include nervous system tumors and ocular abnormalities (3). We present a case in an 18-year-old man affected by NF2 with a gastric plexiform schwannoma, which was confirmed by endoscopic biopsy. To our knowledge, the case we present is the first report of a patient affected by NF2 with extremely rare case of gastric schwannoma. CASE REPORT