Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Dynamic activation of apoptosis: conformational ensembles of cIAP1 are linked to a spring-loaded mechanism

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • الموضوع:
      2014
    • نبذة مختصرة :
      cIAP1 undergoes a dramatic conformational change during activation that is now shown to be due to the dynamic and metastable nature of the closed form of the enzyme. The discovery of such a striking mechanism for functional control was enabled by state-of-the-art enzymological and biophysical methods.
    • ISSN:
      1545-9985
    • Rights:
      OPEN
    • الرقم المعرف:
      edsair.doi.dedup.....bda4f8708d23192d653a6ceac9b82d02