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The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study

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  • معلومة اضافية
    • Contributors:
      Mazzinari G.; Serpa Neto A.; Hemmes S.N.T.; Hedenstierna G.; Jaber S.; Hiesmayr M.; Hollmann M.W.; Mills G.H.; Vidal Melo M.F.; Pearse R.M.; Putensen C.; Schmid W.; Severgnini P.; Wrigge H.; Cambronero O.D.; Ball L.; de Abreu M.G.; Pelosi P.; Schultz M.J.; Kroell W.; Metzler H.; Struber G.; Wegscheider T.; Gombotz H.; Urbanek B.; Kahn D.; Momeni M.; Pospiech A.; Lois F.; Forget P.; Grosu I.; Poelaert J.; van Mossevelde V.; van Malderen M.-C.; Dylst D.; van Melkebeek J.; Beran M.; de Hert S.; De Baerdemaeker L.; Heyse B.; Van Limmen J.; Wyffels P.; Jacobs T.; Roels N.; De Bruyne A.; van de Velde S.; Leva B.; Damster S.; Plichon B.; Juros-Zovko M.; Djonovic-Omanovic D.; Pernar S.; Zunic J.; Miskovic P.; Zilic A.; Kvolik S.; Ivic D.; Azenic-Venzera D.; Skiljic S.; Vinkovic H.; Oputric I.; Juricic K.; Frkovic V.; Kopic J.; Mirkovic I.; Karanovic N.; Carev M.; Dropulic N.; Saric J.P.; Erceg G.; Dvorscak M.B.; Mazul-Sunko B.; Pavicic A.M.; Goranovic T.; Maldini B.; Radocaj T.; Gavranovic Z.; Mladic-Batinica I.; Sehovic M.; Stourac P.; Harazim H.; Smekalova O.; Kosinova M.; Kolacek T.; Hudacek K.; Drab M.; Brujevic J.; Vitkova K.; Jirmanova K.; Volfova I.; Dzurnakova P.; Liskova K.; Dudas R.; Filipsky R.; el Kafrawy S.; Abdelwahab H.H.; Metwally T.; Abdel-Razek A.; El-Shaarawy A.M.; Hasan W.F.; Ahmed A.G.; Yassin H.; Magdy M.; Abdelhady M.; Mahran M.; Herodes E.; Kivik P.; Oganjan J.; Aun A.; Sormus A.; Sarapuu K.; Mall M.; Karjagin J.; Futier E.; Petit A.; Gerard A.; Marret E.; Solier M.; Prades A.; Krassler J.; Merzky S.; Uhlig C.; Kiss T.; Bundy A.; Bluth T.; Gueldner A.; Spieth P.; Scharffenberg M.; Thiem D.T.; Koch T.; Treschan T.; Schaefer M.; Bastin B.; Geib J.; Weiss M.; Kienbaum P.; Pannen B.; Gottschalk A.; Konrad M.; Westerheide D.; Schwerdtfeger B.; Simon P.; Reske A.; Nestler C.; Valsamidis D.; Stroumpoulis K.; Antholopoulos G.; Andreou A.; Karapanos D.; Theodoraki K.; Gkiokas G.; Tasoulis M.-K.; Sidiropoulou T.; Zafeiropoulou F.; Florou P.; Pandazi A.; Tsaousi G.; Nouris C.; Pourzitaki C.; Bystritski D.; Pizov R.; Eden A.; Pesce C.V.; Campanile A.; Marrella A.; Grasso S.; De Michele M.; Bona F.; Giacoletto G.; Sardo E.; Giancarlo L.; Sottosanti V.; Solca M.; Volta C.A.; Spadaro S.; Verri M.; Ragazzi R.; Zoppellari R.; Cinnella G.; Raimondo P.; La Bella D.; Mirabella L.; D'antini D.; Molin A.; Brunetti I.; Gratarola A.; Pellerano G.; Sileo R.; Pezzatto S.; Montagnani L.; Pasin L.; Landoni G.; Zangrillo A.; Beretta L.; Di Parma A.L.; Tarzia V.; Dossi R.; Sassone M.E.; Sances D.; Tredici S.; Spano G.; Castellani G.; Delunas L.; Peradze S.; Venturino M.; Arpino I.; Sher S.; Tommasino C.; Rapido F.; Morelli P.; Vargas M.; Servillo G.; Cortegiani A.; Raineri S.M.; Montalto F.; Russotto V.; Giarratano A.; Baciarello M.; Generali M.; Cerati G.; Leykin Y.; Bressan F.; Bartolini V.; Zamidei L.; Brazzi L.; Liperi C.; Sales G.; Pistidda L.; Brugnoni E.; Musella G.; Bacuzzi A.; Muhardri D.; Gecaj-Gashi A.; Sada F.; Bytyqi A.; Karbonskiene A.; Aukstakalniene R.; Teberaite Z.; Salciute E.; Tikuisis R.; Miliauskas P.; Jurate S.; Kontrimaviciute E.; Tomkute G.; Xuereb J.; Bezzina M.; Borg F.J.; Hemmes S.; Hollmann M.; Wiersma I.; Binnekade J.; Bos L.; Boer C.; Duvekot A.; in 't Veld B.; Werger A.; Dennesen P.; Severijns C.; De Jong J.; Hering J.; van Beek R.; Ivars S.; Jammer I.; Breidablik A.; Hodt K.S.; Fjellanger F.; Avalos M.V.; Mellin-Olsen J.; Andersson E.; Shafi-Kabiri A.; Molina R.; Wutai S.; Morais E.; Tareco G.; Ferreira D.; Amaral J.; de Lurdes Goncalves Castro M.; Cadilha S.; Appleton S.; Parente S.; Correia M.; Martins D.; Monteirosa A.; Ricardo A.; Rodrigues S.; Horhota L.; Grintescu I.M.; Mirea L.; Grintescu I.C.; Corneci D.; Negoita S.; Dutu M.; Garotescu I.P.; Filipescu D.; Prodan A.B.; Droc G.; Fota R.; Popescu M.; Tomescu D.; Petcu A.M.; Tudoroiu M.I.; Moise A.; Guran C.-T.; Gherghina I.; Costea D.; Cindea I.; Copotoiu S.-M.; Copotoiu R.; Barsan V.; Tolcser Z.; Riciu M.; Moldovan S.G.; Veres M.; Gritsan A.; Kapkan T.; Gritsan G.; Korolkov O.; Kulikov A.; Lubnin A.; Ovezov A.; Prokoshev P.; Lugovoy A.; Anipchenko N.; Babayants A.; Komissarova I.; Zalina K.; Likhvantsev V.; Fedorov S.; Lazukic A.; Pejakovic J.; Mihajlovic D.; Kusnierikova Z.; Zelinkova M.; Bruncakova K.; Polakovicova L.; Sobona V.; Novak-Supe B.; Pekle-Golez A.; Jovanov M.; Strazisar B.; Markovic-Bozic J.; Novak-Jankovic V.; Voje M.; Grynyuk A.; Kostadinov I.; Spindler-Vesel A.; Moral V.; Unzueta M.C.; Puigbo C.; Fava J.; Canet J.; Moret E.; Rodriguez Nunez M.; Sendra M.; Brunelli A.; Rodenas F.; Monedero P.; Martinez F.H.; Temino M.J.Y.; Martinez Simon A.; de Abajo Larriba A.; Lisi A.; Perez G.; Martinez R.; Granell M.; Vivo J.T.; Ruiz C.S.; de Andres Ibanez J.A.; Pastor E.; Soro M.; Ferrando C.; Defez M.; Alvares-Santullano C.A.; Perez R.; Rico J.; Jawad M.; Saeed Y.; Gillberg L.; Bengisun Z.K.; Kazbek B.K.; Coskunfirat N.; Boztug N.; Sanli S.; Yilmaz M.; Hadimioglu N.; Senturk N.M.; Camci E.; Kucukgoncu S.; Sungur Z.; Sivrikoz N.; Ozgen S.U.; Toraman F.; Selvi O.; Senturk O.; Yildiz M.; Kuvaki B.; Gunenc F.; Kucukguclu S.; Ozbilgin S.; Maral J.; Canli S.; Arun O.; Saltali A.; Aydogan E.; Akgun F.N.; Sanlikarip C.; Karaman F.M.; Mazur A.; Vorotyntsev S.; Rousseau G.; Barrett C.; Stancombe L.; Shelley B.; Scholes H.; Limb J.; Rafi A.; Wayman L.; Deane J.; Rogerson D.; Williams J.; Yates S.; Rogers E.; Pulletz M.; Moreton S.; Jones S.; Venkatesh S.; Burton M.; Brown L.; Goodall C.; Rucklidge M.; Fuller D.; Nadolski M.; Kusre S.; Lundberg M.; Everett L.; Nutt H.; Zuleika M.; Carvalho P.; Clements D.; Creagh-Brown B.; Watt P.; Raymode P.; Pearse R.; Mohr O.; Raj A.; Creary T.; Chishti A.; Bell A.; Higham C.; Cain A.; Gibb S.; Mowat S.; Franklin D.; West C.; Minto G.; Boyd N.; Mills G.; Calton E.; Walker R.; Mackenzie F.; Ellison B.; Roberts H.; Chikungwa M.; Jackson C.; Donovan A.; Foot J.; Homan E.; Montgomery J.; Portch D.; Mercer P.; Palmer J.; Paddle J.; Fouracres A.; Datson A.; Andrew A.; Welch L.; Rose A.; Varma S.; Simeson K.; Rambhatla M.; Susarla J.; Marri S.; Kodaganallur K.; Das A.; Algarsamy S.; Colley J.; Davies S.; Szewczyk M.; Smith T.; Fernandez-Bustamante A.; Luzier E.; Almagro A.; Melo M.V.; Fernando L.; Sulemanji D.; Sprung J.; Weingarten T.; Kor D.; Scavonetto F.; Tze Y.; Anesthesiology research group; Supporting clinical sciences; Anesthesiology; Guido, Mazzinari; Ary Serpa, Neto; Sabrine N, T Hemme; Goran, Hedenstierna; Samir, Jaber; Michael, Hiesmayr; Markus, W Hollmann; Gary, H Mill; Marcos, F Vidal Melo; Rupert, M Pearse; Christian, Putensen; Werner, Schmid; Paolo, Severgnini; Hermann, Wrigge; Oscar Diaz, Cambronero; Lorenzo, Ball; Marcelo Gama de, Abreu; Paolo, Pelosi; Marcus, J Schultz (LAS VEGAS study–investigator; PROtective VEntilation, Network; Clinical Trial Network of the European Society of, Anaesthesiology); Zangrillo, A; Landoni, G; Beretta, L; Physiologie & médecine expérimentale du Cœur et des Muscles [U 1046] (PhyMedExp); Université de Montpellier (UM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS); Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier); Pulmonary medicine; IOO; ACS - Microcirculation; ACS - Heart failure & arrhythmias; ACS - Diabetes & metabolism; study–investigators, LAS VEGAS; NETwork, PROtective VEntilation; Anaesthesiology, Clinical Trial Network of the European Society of; Mazzinari, Guido; Serpa Neto, Ary; Hemmes, Sabrine N T; Hedenstierna, Goran; Jaber, Samir; Hiesmayr, Michael; Hollmann, Markus W; Mills, Gary H; Vidal Melo, Marcos F; Pearse, Rupert M; Putensen, Christian; Schmid, Werner; Severgnini, Paolo; Wrigge, Hermann; Cambronero, Oscar Diaz; Ball, Lorenzo; de Abreu, Marcelo Gama; Pelosi, Paolo; Schultz; Marcus, J; Servillo, G; Vargas, M; Intensive Care Medicine; APH - Quality of Care; ACS - Pulmonary hypertension & thrombosis; Pulmonology; APH - Global Health
    • بيانات النشر:
      BioMed Central Ltd, 2021.
    • الموضوع:
      2021
    • نبذة مختصرة :
      Background It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events. Methods Posthoc retrospective propensity score–weighted cohort analysis of patients undergoing open or closed abdominal surgery in the ‘Local ASsessment of Ventilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study, that included patients in 146 hospitals across 29 countries. The primary endpoint was a composite of PPCs. The secondary endpoint was a composite of intraoperative adverse events. Results The analysis included 1128 and 906 patients undergoing open or closed abdominal surgery, respectively. The PPC rate was 5%. ΔP was lower in open abdominal surgery patients, but ΔPTW was not different between groups. The association of ΔPTW with PPCs was significant in both groups and had a higher risk ratio in closed compared to open abdominal surgery patients (1.11 [95%CI 1.10 to 1.20], P P P TW with intraoperative adverse events was also significant in both groups but had higher odds ratio in closed compared to open abdominal surgery patients (1.13 [95%CI 1.12– to 1.14], P P P Conclusions ΔP is associated with PPC and intraoperative adverse events in abdominal surgery, both in open and closed abdominal surgery. Trial registration LAS VEGAS was registered at clinicaltrials.gov (trial identifier NCT01601223).
    • File Description:
      application/pdf
    • ISSN:
      1471-2253
    • Rights:
      OPEN
    • الرقم المعرف:
      edsair.doi.dedup.....b7c355192fcae0483c6259e35ba72eff