Item request has been placed! ×
Item request cannot be made. ×
loading  Processing Request

Synthesis of Novel Cyclic Nitrones with gem ‐Difluoroalkyl Side Chains Through Cascade Reactions

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
اقرأ على الانترنت اقرأ أكثر حفظ في قائمتي
  • معلومة اضافية
    • Contributors:
      Institut des Sciences Chimiques de Rennes (ISCR); Université de Rennes (UR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes); Institut National des Sciences Appliquées (INSA)-Institut National des Sciences Appliquées (INSA)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS); Lebanese University [Beirut] (LU); Research Grant program at Lebanese University; French CNRS Centre National de la Recherche Scientifique (CNRS); University of Rennes 1 (CNRS UMR 6226); National Council for Scientific Research of Lebanon (CNRS-L); Agence Universitaire de la Francophonie (AUF); Lebanese University (UL); Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)-Université de Rennes 1 (UR1); Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-Ecole Nationale Supérieure de Chimie de Rennes (ENSCR)-Institut National des Sciences Appliquées - Rennes (INSA Rennes); Institut National des Sciences Appliquées (INSA)-Université de Rennes (UNIV-RENNES)-Institut National des Sciences Appliquées (INSA)
    • بيانات النشر:
      Wiley, 2020.
    • الموضوع:
      2020
    • نبذة مختصرة :
      International audience; New five-membered cyclic nitrones withgem-difluoroalkyl groups in gamma-position have been prepared by a 3-step sequence starting from propargylic alcohols. This domino process involves a base-mediated isomerization reaction to enones, which are trapped in situ by nitroalkane anions. In a final step, starting from these key precursors, a reduction-cyclization process affords the target molecules. Mono- and bicyclic nitrones have been prepared by this route which allows, as well, the synthesis of nitrones with functional groups in terminal position of the side chain.
    • ISSN:
      1099-0690
      1434-193X
    • الرقم المعرف:
      10.1002/ejoc.202000972
    • الرقم المعرف:
      10.1002/ejoc.202000972⟩
    • Rights:
      OPEN
    • الرقم المعرف:
      edsair.doi.dedup.....96697373a28a69ce5c56d11317e753dd