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Angiotensin Converting Enzyme (ACE): A Marker for Personalized Feedback on Dieting

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  • معلومة اضافية
    • الموضوع:
      2020
    • نبذة مختصرة :
      Angiotensin Converting Enzyme (ACE) expression and activity is associated with obesity. ACE is a circulating factor that predicts sustained weight loss over a time frame of months. Here, we evaluate whether ACE might also be an early marker (over a 24-hour period) for weight loss. 32 participants (78% females
      BMI 28.47 ±
      4.87kg/m2) followed a 1200KCal diet with an optional daily (<
      250KCal) snack and were asked to use an in-house generated health platform to provide recordings of food intake, physical activity and urine collection time and volume. Following a day of dieting, ACE levels in urine negatively correlated with weight loss (p = 0.015 ). This reduction in ACE levels was significantly more robust in individuals with a BMI >
      25 (p = 0.0025 ). This study demonstrated that ACE levels correlate with BMI and weight loss as early as after 1 day of dieting, and thus ACE could be a potential early &ldquo
      biofeedback&rdquo
      marker for weight loss and diet efficiency.
    • File Description:
      application/pdf
    • ISSN:
      2072-6643
    • Rights:
      OPEN
    • الرقم المعرف:
      edsair.doi.dedup.....51f995425dab9bb50c8fa793a13de309