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A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death

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المؤلفون: Ryan J. Watts; Richard Mayeux; Timothy W. Behrens; Oded Foreman; Ward Ortmann; Gerard D. Schellenberg; Julie Hunkapiller; Lindsay A. Farrer; Susan M Sa; Robert R. Graham; Tushar Bhangale; Murat Yaylaoglu; Carlos Cruchaga; Jasvinder K. Atwal; Jonathan L. Haines; Nisha Rathore; Karpagam Srinivasan; Margaret A. Pericak-Vance; Marc Tessier-Lavigne; Janice A. Maloney; David V. Hansen; Alison Goate; Monica K Wetzel-Smith
المصدر:
Nature Medicine. 20:1452-1457
الموضوع:
Programmed cell death; Mutation; HEK 293 cells; Late onset; General Medicine; Disease; Biology; UNC5C; medicine.disease; medicine.disease_cause; General Biochemistry, Genetics and Molecular Biology; Immunology; medicine; Alzheimer's disease
الدخول الالكتروني :
https://explore.openaire.eu/search/publication?articleId=doi_________::ba6d1694b0f4fcc3b849cfaaf240338c
https://doi.org/10.1038/nm.3736

معلومة اضافية
- بيانات النشر:
  Springer Science and Business Media LLC, 2014.
- الموضوع:
  2014
- نبذة مختصرة :
  Mutations in UNC5C are identified in individuals with late-onset Alzheimer's disease and increase susceptibility of neurons to cell death.
- ISSN:
  1546-170X
  1078-8956
- Rights:
  OPEN
- الرقم المعرف:
  edsair.doi...........ba6d1694b0f4fcc3b849cfaaf240338c

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