نبذة مختصرة : Purpose. To evaluate the efficacy and safety of myopia correction by the TransPRK method using therapeutic soft contact lens (SCL) impregnated with a 0.1 % dexamethasone solution Material and methods. A prospective, controlled study included 32 patients (64 eyes). The left eyes were combined into the “With DEX” study group, the right ones into the “Without DEX” control group. After the TransPRK was performed, SCL soaked with dexamethasone was put on the eyes of the “With DEX” group. The same SCL without impregnation was put on the eyes of second group “Without DEX”. Results. 1 and 3 months after, the operation there were no significant differences in UDVA between the groups. Mean UDVA 3 months after the operation in the group “With DEX” was 1.0 ± 0, in the group “Without DEX” 1.0 ± 0.1 (p-value = 0.625). There were no significant differences in the rate of formation of the refractive result, its predictability and stability. After 1 month in the “Without DEX” group, the difference in the level of UDVA before surgery and CDVA after was the same (without loss of the number of lines read) in 44 %, in the “With DEX” group, in 67 % (p-value = 0.607). The same picture was observed after 3 months, in the group "With DEX" – in 83 %, “Without DEX” – in 61 % (p-value = 0.607). The difference is not statistically significant, but there was a trend towards an accelerated recovery of UDVA in the “With DEX” group. The pain syndrome was significantly less in the “With DEX” group (p-value = 0.021). There were no significant differences in the epithelialization time between groups, as well as subepithelial fibroplasia. Conclusion. According to the results obtained, TransPRK with therapeutic SCL impregnated with dexamethasone can be considered as an effective and safe method, which also makes possible to reduce pain in the early postoperative period without delaying epithelialization. Keywords: dexamethasone, corneal syndrome, photorefractive keratotomy, therapeutic lens.
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