Physicochemical Properties of Protoporphyrin IX by Metal Ions in Acetonitrile-Water Mixture Solution

Porphyrin derivatives contain pyrrole rings, five membered heterocycles. These compounds have properties of a conjugated diene and of an amine. Delocalization of π electrons stabilizes the ring and their ultra-violet absorption maximum peak shifts to a longer wavelength. They can easily absorb visible light, and thus can utilize sunlight directly as a good photosensitizer. Re-cently, photodynamic therapy has been used in the management of various malignant tumors, including cancers of the skin, gas-trointestinal tract, lung and uterus.