Characterization of Two Site-specifically Mutated Human Dihydrolipoamide Dehydrogenase (Leu-46 to Ala and Pro-52 to Val)

Comparison of amino acid sequences around active disulfide center regions of dihydrolipoamide dehydrogenases. The Leu-46 and Pro-52 residues in human E3 and the corresponding residues in other E3s are indicated by underlines.Sources Amino acid sequenceHuman GGTCLNVGCIPTrypanosoma brucei GGTCLNVGCIPPisum sativum GGTCL NVGCIPSaccharomyces cerevisiae GGTCLNVGCIPPseudomonas putida (lpdg) GGTCL NVGCIPAzotobacter vinelandii GGTCLNVGCIPEscherichia coli GGTCL NVGCIPSus scrofa GGTCL NVGCIP Canis familiaris GGTCL NVGCIP Mus musculus GGTCL NVGCIP Trypanosoma brucei GGTCL NVGCIP Trypanosoma cruzi GGTCL NVGCIP Pisum sativum GGTCL NVGCIP Manduca sexta GGTCL NVGCIP Schizosaccharomyces pombe GGTCL NVGCIP Pseudomonas putida (lpd3) GGTCL NVGCMP Pseudomonas fluorescens GGTCL NVGCIP Rhodobacter capsulatus GGTCL NVGCIP Alcaligenes eutrophus GGTCL NVGCIPHaemophilus influenzae GGVCLNVGCIPBacillus stearothermophilus GGVCL NVGCIP Bacillus subtilis GGVCL NVGCIP Staphylococcus aureus GGVCL NVGCIP Vibrio parahaemolyticus GGVCL NVGCIP Mycoplasma pneumoniae GGVCL NVGCIP Mycoplasma genitalium GGVCL NVGCIP Pseudomonas putida (lpdv) GGTCL NIGCIP Chlamydia trachomatis GGTCL NRGCIP Chlamydia pneumoniae GGTCL NRGCIP Halobacterium volcanii GGTCL NYGCIP Bacillus subtilis (acol) GGTCL NEGCIP Bacillus subtilis (bfmbc) GGTCL HKGCIPAcholeplasma laidlawii GGICL NHGCIP Zymomonas mobilis GGICL NWGCIPSynechocytis sp. GGTCV NRGCIP Chlorobium vibrioforme GGVCV NWGCIP